Sulfonamides and Potentiated Sulfonamides

Question 1

*What are Sulfonamides considered to be?

Answer 1

one of the oldest groups of antibiotics used in animals

Question 2

Examples of Sulfonamides

Answer 2

1. Sulfadimethoxine
2. Sulfamethazine
3. Sulfachlorpyridazine

Question 3

Examples of Potentiated Sulfonamides

Answer 3

1. Sulfadiazine-timethoprim

2. Sulfadimethoxine-ormetoprim

Question 4

*What is a Potentiated Sulfonamide?

Answer 4

Combining a sulfonamide with another antibiotic to increases the spectrum of activity

Question 5

*How do sulfonamides effect bacteria?

Answer 5

interferes with the formation of folic acid of bacteria

can’t make DNA or RNA

Question 6

How are sulfonamides absorbed into the body?

Answer 6

oral administration

Question 7

How are sulfonamides distributed throughout the body?

Answer 7

• all body tissues

- not CNS

Question 8

Where is this drug metabolized?

Answer 8

liver

Question 9

Where is this drug eliminated from the body?

Answer 9

• metabolites in urine

- unchanged molecules in urine

Question 10

*What are sulfonamides used against?

Answer 10

1. G+ and G-

2. Some Protozoa

Question 11

*What is KCS?

Answer 11

• Keratoconjuntivitis sicca

- causes permanent dry eye

Question 12

*What are Potentiated Sulfonamides used for?

Answer 12

UTI in mostly large animals

Question 13

*What is the drug “Albon” used for?

Answer 13

• used in small animals for coccidian infections in dogs and cats
• treats diarrhea