Quinolones Flashcards
1
Q
What is the newest antibiotic group?
A
quinolones
2
Q
When should quinolones be used?
A
Reserve use for treatment of more serious infections
3
Q
Examples of Quinolones
A
- Enrofloxacin
- Marbofloxacin
- Orbifloxacin
- Ciprofloxacin
4
Q
*How do quinones control bacterial growth?
A
disruption of bacterial DNA molecule
5
Q
*How are quinones absorbed?
A
- oral and parenteral administration
- GI absorption poor in ruminants
- slow absorption with food
6
Q
How are quinones distributed in the body?
A
- penetrates most tissues
2. Not CNS
7
Q
How are quinones eliminated from the body?
A
metabolites are excreted in urine and bile
8
Q
Where are quinones metabolized?
A
liver
9
Q
What bacteria are quinones used against?
A
Most G- and some G+ bacteria
10
Q
What do quinones not work against?
A
anaerobic bacteria
11
Q
*What are the side effects of using quinolones?
A
- can cause damage to articular cartilage of growing animals
- may cause crystals to form in the urine
- vomiting, diarrhea, nausea
12
Q
What animals should you not use quinones?
A
pregnant animals
