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Pharmacology > Cephalosporins > Flashcards

Cephalosporins Flashcards

1
Q

What kind of properties do cephalosporins have?

A

Similar as penicillin

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2
Q

Examples of cephalosporins

A
  1. Cephalexin
  2. Cefazolin
  3. Cefadroxil
  4. Cephapirin
  5. Ceftiofur (3rd generation)
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3
Q

*What kind of drug is Convenia (cefovecin)?

A

Semi-synthetic
Broad spectrum
Two week injectable

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4
Q

*What is Convenia (cefovecin) used for?

A
  • skin issues in dogs and cats

- UTI in cats

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5
Q

*What is Convenia (cefovecin) not effective against?

A

Pseudomonas

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6
Q

*What type of drug is Cefpodoxime (Simplicef)?

A

Oral anabiotic

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7
Q

How frequently is Cefpodoxime (Simplicef) administered?

A

Once a day

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8
Q

*What is Cefpodoxime (Simplicef)used for?

A

Skin infections

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9
Q

How do cephalosporins control the growth bacteria?

A

Inhibit the formation of the cell wall in actively growing bacteria

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10
Q

How are cephalosporins absorbed?

A
  • observed well after parenteral and oral administration

- Absorbed slowly in the presence of food

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11
Q

How are cephalosporins distributed in the body?

A

Distributes well to all tissues except CNS

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12
Q

How are cephalosporins metabolized and eliminated from the body?

A

Excreted by the kidneys either unchanged or after being metabolized by the liver

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13
Q

What is the spectrum of activity for first generation cephalosporins?

A

G+ bacteria

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14
Q

What is the spectrum of activity for second generation cephalosporins?

A

G+ bacteria

Some G- bacteria

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15
Q

*What are cephalosporins ineffective against?

A

Penicillin resistant bacteria

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16
Q

*What are the precautions for using cephalosporins?

A

Possible allergic reaction

May cause pain when injected IM

17
Q

What are the possible allergic reaction’s from cephalosporins?

A
  1. Fever
  2. Swollen lymph nodes
  3. Facial swelling
  4. Skin rash
  5. Shock
18
Q

What can oral administration of cephalosporins cause?

A

Vomiting
Diarrhea
Anorexia

19
Q

*What should you not use cephalosporins with?

A

Bacteriostatic antibiotics

20
Q

*When can cephalosporins become potentially toxic to the kidneys?

A

If overdosed

21
Q

What should you observe after you are finished administering cephalosporins to animal?

A

Withdrawal times

Pharmacology (74 decks)

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