Drug Effect Flashcards
1
Q
How are drugs able to be effective?
A
Drugs must combine with cellular receptors to exert their effect
2
Q
How do drugs have an effect on specific tissues?
A
drugs have an effect on tissues that have receptors they can bind to
3
Q
Does the tendency of a drug to bind to a receptor always produce the desired effect?
A
no, its ability to produce the desired effect can vary depending on compatibility of a drug to a receptor
4
Q
What are the types of cellular effects observed after a drug binds to a receptor?
A
- Secretion of a substance (GnRH)
- Contraction of muscle cells (Epinephrine)
- Cell death (lysodren)
5
Q
What are the non-receptor mediated drug effects?
A
- Drugs exert their effect without binding to a receptor
- Mannitol
- EDTA
- Antacids
6
Q
What does mannitol do?
A
draws water into tubule
7
Q
What does EDTA do?
A
combines with calcium to prevent clotting
8
Q
Antacids
A
- Ca, Mg, Al -OH
2. Combine with HCl to prevent heartburn
