Avermectins Flashcards

1
Q

What are Avermectins considered to be?

A

a popular antiparasitic used in large animals

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2
Q

Examples of Avermectins

4

A
  1. ivermectin
  2. moxidectin
  3. doramectin
  4. selamectin (Revolution)
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3
Q

How do Avermectins effect parasites?

A

kills parasites by interfering with their CNS

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4
Q

What animals are Avermectins mostly used for?

A

large animals

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5
Q

What type of parasites are Avermectins used against? (2)

A
  1. internal

2. external

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6
Q

What are Avermectins effective against in horses? (4)

A
  1. bots
  2. ascarids
  3. strongyles
  4. pinworms
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7
Q

What are Avermectins effective against in cattle? (3)

A
  1. trichostrongyles
  2. lungworms
  3. sucking lice
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8
Q

What are Avermectins effective against in swine? (4)

A
  1. ascarids
  2. strongyles
  3. lungworms
  4. mites
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9
Q

What are Avermectins effective against in dogs and cats? (4)

A
  1. heartworm microfilaria
  2. acarids and hookworms in cats
  3. fleas
  4. mites
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10
Q

What breeds of dog can you not use Avermectins on?

A
  1. Collies
  2. Shelties
  3. Australian Shepherds
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11
Q

Why can’t specific breeds of dogs have Avermectins?

A

they lack a gene MDR-1 that helps remove drugs from the CNS (genetic mutation)

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12
Q

What are the precautions for using Avermectins in horses and cattle?

A

can develop inflammatory reaction to dead parasites

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