Succinylcholine

Question 1

Succinylcholine: Generic Name

Answer 1

Succinylcholine chloride

Question 2

Succinylcholine: Trade Name

Answer 2

Anectine

Question 3

Succinylcholine: Class

Answer 3

Neuromuscular blocking agent (depolarizing), anesthesia adjunct, skeletal muscle relaxant

Question 4

Succinylcholine: Action

Answer 4

An ultra-short-acting depolarizing skeletal muscle relaxant. Causes paralysis by interfering with neural transmission at the myoneural junction. Depolarization of the drug maybe observed as fasciculations. Onset of action is within 0.5 to 1 minute. Duration of peak effect is 4 to 10 minutes.

Question 5

Succinylcholine: Indications

Answer 5

Provide skeletal muscle relaxation (paralysis) to facilitate endotracheal intubation during RSI

Question 6

Succinylcholine: Contraindications

Answer 6

Hypersensitivity, hx or family hx of malignant hyperthermia, severe burns, crush injuries, glaucoma, penetrating eye injuries, and significant neuromuscular disease

Question 7

Succinylcholine: S. E.

Answer 7

Muscle pain from fasciculations, rhabdomyolysis, myoglobinuria, excessive salivation, (blocked by atropine) prolonged respiratory depression, hypotension, bradycardia, (in children) ↑ ICP, (transient) and Malignant hyperthermia

Question 8

Succinylcholine: Supplied

Answer 8

Vial of 10 ml— (20 mg/ml)

Question 9

Succinylcholine: Adult Dose

Answer 9

1-1.5 mg/kg IV, may repeat once as needed

Question 10

Succinylcholine: Pedi Dose

Answer 10

1-1.5mg/kg IV/IO may repeat once as needed

INFANTS: 2mg/kg

Question 11

Succinylcholine: Precautions

Answer 11

Consider premedication with atropine and lidocaine, pre-sedate patient prior to paralysis