2-Pam

Question 1

2-PAM: generic name

Answer 1

Pralidoxime

Question 2

2-PAM: trade name

Answer 2

2-PAM

Question 3

2-PAM: class

Answer 3

Cholinesterase reactivator, antidote

Question 4

2-PAM: action

Answer 4

Reactivates cholinesterase to effectively act as an antidote to organophosphate and pesticide poisonings. This allows for destruction of accumulated acetylcholine at the neuromuscular junction resulting in reversal of respiratory and skeletal muscle paralysis

Question 5

2-PAM: indications

Answer 5

Rx of organophosphate or pesticide exposure/poisonings

Question 6

2-PAM: contraindications

Answer 6

Reduced dose with impaired renal function

Question 7

2-PAM: S. E.

Answer 7

Dizziness, HA, neuromuscular blockade, seizure, laryngospasm, hyperventilation, apnea, tachycardia, cardiac arrest, nausea, rash, pain at injection site

Question 8

2-PAM: supplied

Answer 8

Auto-injector with 600 mg in 2mL

Question 9

2-PAM: adult dose

Answer 9

Auto injector IM, may be repeated PRN q 15m

Question 10

2-PAM: precautions

Answer 10

Most effective ASAP after exposure