Epinephrine

Question 1

Epi: Generic Name

Answer 1

Epinephrine

Question 2

Epi: Trade Name

Answer 2

Adrenalin

Question 3

Epi: Classification

Answer 3

Sympathomimetic, cardiac stimulant, bronchodilator, antiallergic, vasopressor (constricts blood vessels).

Question 4

Epi: Action

Answer 4

Stimulates alpha and beta adrenergic receptors. Strengthens heart to contract harder and faster. Vasoconstriction effect that causes more blood flow during CPR for heart and brain.

Question 5

Epi: Indications

Answer 5

Cardiac arrest, VF, pulseless VT, Asystole, PEA, Anaphylaxis, or asthma (COPD).

Question 6

Epi: Contraindications

Answer 6

Not going to use for beta blocker overdose and only anaphylactic shock.

Question 7

Epi: Side Effects

Answer 7

Nervousness, tremors, dizziness, weakness, HA, and tachycardia

Question 8

Epi: How Supplied

Answer 8

Prefilled syringed 0.1mg/ml (1:10,000), total of 10cc=1mg.

Multidose vial 1mg/ml (1:1,000)

Question 9

Epi: Dosage: Adult

Answer 9

Cardiac arrest: 1mg (10mL of 1:10,000 solution) administered q 3-5m during resuscitation. Tracheal route: 2mg diluted in 10 mL normal saline (NS).

Anaphylaxis: 0.3-0.5mg (1:1,000 IM or SQ
0.3-0.5mg IV of 1:10,000 dilution if hypotension or poor perfusion.

Asthma w/ severe bronchoconstriction: 0.3-0.5mg SQ of 1:1,000

Question 10

Epi: Dosage: Peds

Answer 10

Cardiac arrest: (1:10,000) Give 0.01 mg/kg up to 1mg IV or IO. Tracheal route: (1:1,000) Give 0.1mg/kg or 0.1cc/kg up to 10cc.

Anaphylaxis: (1:1,000) 0.01mg/kg SQ or IM up to 0.3mg if pt was exposed to commonly recognized allergen and has respiratory distress or hypotension.

Question 11

Epi: Precautions

Answer 11

Pregnancy safety, cat. C.
Raising BP and ↑ HR may cause myocardial ischemia, angina, and ↑ myocardial O2 demand. Higher doses may be required to Rx poison/drug-induced shock. Do not use concurrently w/Brevibloc. The effects of drug may be potentiated by tricyclic antidepressants.