Amiodarone

Question 1

Amiodarone: Generic Name

Answer 1

Amiodarone Hydrcholride

Question 2

Amiodarone: Trade Name

Answer 2

Cadarone

Question 3

Amiodarone: Classification

Answer 3

Antiarrthythmic

Question 4

Amiodarone: Actions

Answer 4

Blocks sodium channels at rapid pacing frequencies. Delays repolarization and ↑ duration of action potential. After IV use, it relaxes vascular and smooth muscle, reduces peripheral vascular resistance (afterload). Slows HR because it blocks sodium channels

Question 5

Amiodarone: Indications

Answer 5

VF and pulseless VT after defib. Stable VT and unstable VT after cardioversion

Question 6

Amiodarone: Contraindications

Answer 6

AV blocks, hypersensitivity, cardiogenic shock, bradycardia

Question 7

Amiodarone: S.E.

Answer 7

Cough and progressive dyspnea. Worsening of arrhythmias, symptomatic bradycardia, sinus arrest, SA node dysfunction, CHF edema, hypotension, cardiac arrest, HA, N/V, abd pain, shock

Question 8

Amiodarone: Supplied

Answer 8

50mg/mL vials and prefilled syringes

Question 9

Amiodarone: Adult Dose

Answer 9

Pulseless VF/VT: 300mg IVP, consider repeating once 150mg IVP in 3-5m.

Wide complex tachycardia (stable): 150 mg rapid infusion IV (15mg/min) over first 10 minutes.
May repeat 150mg rapid infusion IV q 10m PRN

Question 10

Amiodarone: Ped Dose

Answer 10

Pulseless VF/VT: 5mg/kg IV/IO bolus.

Perfusing VT: 5mg/kg IV/IO over 20-60m

Question 11

Amiodarone: Precautions

Answer 11

Pregnancy safety: Cat. D.

May produce vasodilation and hypotension. May have - inotropic effects May prolong QT interval.