Magnesium Sulfate Flashcards
Mag: generic name
Magnesium sulfate
Mag: trade name
Magnesium sulfate
Mag: class
Antiarrhythmetic, electrolyte and anticonvulsant
Mag: action
↓ striated muscle contractions and blocks peripheral neuromuscular transmission by reducing acetylcholine release at myoneural junction. Reverses refractory VF caused by hypomagnesemia and aids in replenishment of intracellular potassium. Manages seizure in eclampsia pts.
Mag: indications
Life threatening ventricular arrhythmias due to digitalis toxicity, refractory VF, pulseless VT, torsades de pointes, preeclampsia and eclampsia, adjunctive to alleviate bronchospasm in acute asthma
Mag: contraindications
Heart block or myocardial damage
Mag: S. E.
CNS depression, hypotension, circulatory collapse, depression of myocardium, sweating, hypothermia, muscle paralysis, respiratory paralysis, suppression of knee jerk reflex, changes in EKG (↑ PRI, ↑ QRS complex, prolonged QT interval
Mag: adult dose
Tosades de pointes: 1-2g IV/IO
VF/Pulseless VT: 1-2g over 1-2m
Eclampsia: 1-4g IV/IO/IM
Mag: pedi dose
25-50mg/kg IV/IO
Mag: precautions
Should be administered cautiously in the presence of a impaired renal failure. Morphine and Valium potentiate respiratory depression when given to pt receiving MGS04. Toxicity level is 10mg/dL