Adenosine

Question 1

Adenosine: Generic Name

Answer 1

Adenosine

Question 2

Adenosine: Trade Name

Answer 2

Adenocard

Question 3

Adenosine: Class

Answer 3

Antiarrhythmic

Question 4

Adenosine: Action

Answer 4

Naturally occurring nucleoside that acts on the AV node to slow conduction and inhibit reentry pathways. Rapidly metabolized– Half-life is 5 seconds

Question 5

Adenosine: Indications

Answer 5

To convert stable narrow tachycardia (SVT) to normal sinus rhythm. Includes SVT associated with accessory bypassed tracts (Wolff–Parkinson–White syndrome). Not effective in converting rapid AF/Atrial flutter. May be helpful in clarifying borderline wide complex rhythms as dosage will not work on VT

Question 6

Adenosine: Contraindications

Answer 6

Hypersensitivity. 2nd or 3rd degree heart block, sick sinus syndrome, or symptomatic bradycardia. Poison or drug induced tachycardia. COPD pts

Question 7

Adenosine: Adult dose

Answer 7

Initial dose: 6mg IV or IO rapid bolus over 1-3 seconds. Followed quickly by 20mL saline flush; Elevate extremity.

Repeat 12mg in 1-2 minutes if needed.

Third dose: 12mg, maybe given in 1-2 minutes.

Question 8

Adenosine: Pedi dose

Answer 8

Initial dose: 0.1 mg/kg (max of 6mg) rapid IV or IO followed by 5-10mL flush of NS

Second dose is 0.2mg/kg, max of 12mg with 5-10mL flush

Question 9

Adenosine: S. E.

Answer 9

Generally short duration and mild. Persistent arrhythmias and bronchospasm

Question 10

Adenosine: Considerations

Answer 10

Could produce bronchoconstriction in patients with asthma. Will produce short-lived asystole