Specific immune respone Flashcards

Naive b-cells, helper t-cells etc

1
Q

Where are B-cell And T-cells formed

A

Bone marrow

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2
Q

Where do B-cells and T-cells mature

A

T-cells - Thymus
B-cells - Bone marrow

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3
Q

Naive B-cell

A

A B-cell that has never encountered an antigen before

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4
Q

First step of the primary immune response

A

The naive B-cell has complementary receptors to the pathogens antigen and so they bind

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5
Q

Second step of the primary immune response

A

The naive B-cell internalises and processes the pathogen and then displays it on the cell surface membrane as a processed antigen

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6
Q

Third step of the primary immune response

A

The processed antigen is complementary to receptors on the helper t-cell so they bind. After the naive b-cell and helper t-cell bind, the helper t-cell releases a chemical which causes the naive b-cell to clone by MITOSIS and differentiate

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7
Q

Forth step of the primary immune response

A

The naive b-cell differentiates into either a plasma cell or a memory b-cell

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8
Q

Role of the plasmsa cell

A

Secretes monoclonal antibodies
These antibodies are complementary to the specific antigen on the pathogen. These antibodies attach to antigens on pathogens and destroy them

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9
Q

Role of memory b-cell

A

The memory cell circulates the blood, ready to divide if the same antigen / pathogen is encountered again

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10
Q

Secondary immune response

A

Much faster as memory b-cells will recognise the specific antigen on the pathogens surface so antibodies will be produced much faster and symptoms / ilness from the pathogen wont happen

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