Digestion and absorption of proteins

Question 1

Three key enzymes

Answer 1

Endopeptidases, exopeptidases and membrane bound dipeptidases

Question 2

Where are these enzymes found

Answer 2

Endopeptidases and exopeptidases found in Stomach and Duodenum
Dipeptidases found in ileum

Question 3

Where are theses enzymes made

Answer 3

Pancreas

Question 4

Endopeptidases

Answer 4

Hydrolyse central peptide bonds to form smaller peptide chains and increase SA and amount of ends
Protein -> Polypeptides

Question 5

Exopeptidases

Answer 5

Hydrolyses peptide bonds at ends to form dipeptides
Polypeptides -> Dipeptides
TIP: Exo = ends /exit

Question 6

Dipeptidases

Answer 6

Hydrolyse peptide bonds between dipeptides to form amino acids
Dipeptides -> Amino acids

Question 7

Hydrochloric acid in stomach

Answer 7

Stomach contains HCl and this denatures proteins tertiary structure breaking ionic bonds, disulphide bridges and hydrogen bonds .
This produces a long chain of polypeptides.
Therefore, endopeptidases can hydrolyse into smaller polypeptides and then exopeptidases hydrolyse terminal ends

Question 8

Absorption of amino acids

Answer 8

Same as monosaccharides