HIV Flashcards

1
Q

HIV turns into what disease

A

AIDS (Acquired Immune Deficiency Syndrome)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Structure of HIV

A

Contains important enzyme in the centre called reverse transcriptase.
Surrounded by lipid envelope like all viruses.
Contains RNA in centre

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

HIV Replication

A

1) Attachment protein binds to helper T-cell
2) HIV protein capsid fuses with the helper T-cell and sends RNA and reverese transcriptase inside the helper t-cell
3)Reverse transcriptase converts viral RNA into DNA
4) Viral DNA enters host cells nucleus
5)Viral DNA is transcribed in viral mRNA
6)Viral mRNA is translated into viral proteins
7) Viral proteins are used to make a new HIV and HIV breaks away from helper T-cell destroying it

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Consequences of helper T-cell death
:(

A

Immune system is unable to activate B-cells, to produce plasma cells to produce antibodies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Decrease in immune system leads to what disease

A

AIDS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Dormant T-cells

A

Sometimes T-cells are dormant for years meaning HIV is not being replicated

This means an infected individual will not develop the symptoms of AIDS straight away

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Transmission of HIV

A

Having unprotected sex with an infected person
Close contact with infected persons blood
Use of infected blood in transfusion
Mother to child (Breast milk)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Treatment of HIV

A

Antiretroviral drugs which reduce viral load in patient to an undetectable level - cannot pass HIV on
Slow replication of virus by blocking enzyme reverse transcriptase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly