SA vaccine Flashcards
what are the types of vaccines?
modified live
killed
recombinant
what is a recombinant vaccine?
parts of a genetic sequence that encode immunogenic proteins is isolated
what are the core canine vaccines for the WSAVA?
distemper
parvovirus
hepatitis
what are the core canine vaccines for the BSAVA?
distemper
parvovirus
hepatitis
leptospirosis
what type of virus is canine distemper?
morbillivirus
what are the systems associated with clinical signs of canine distemper?
respiratory, alimentary, oculi-nasal, neurological, nose/footpad (hyperkeratosis)
what is the route of infection of canine distemper virus?
inhalation
what virus causes canine hepatitis?
adenovirus-1
where does canine hepatitis replicate?
hepatocyte (jaundice and liver failure)
what are the clinical signs of canine hepatitis?
blue eyes, pyrexia, lethargy vomiting/diarrhoea, jaundice
where does canine parvovirus replicate?
rapidly dividing cells (intestinal crypts, bone marrow…)
what abnormalities are seen on haematology of a dog with parvovirus?
neutropenia, lymphopenia
what are some possible non-core vaccine for dogs?
parainfluenza
kennel cough complex
herpes
rabies
what dogs is herpes vaccine licensed for use on?
pregnant bitches (1 week after mating and before parturition)
what are the clinical signs of leptospirosis?
jaundice, haemorrhagic syndrome, uraemic syndrome