Clinical exams and day 1 skills Flashcards
what are some reasons to vaccinate?
responsible pet ownership maintain healthy pet population reduce deaths reduce zoonosis incidence early detection of clinical conditions encourage client education
why must we wait until MDAs (maternally derived antibodies) have decreased before vaccinating?
will inhibit the development of an immune response in the neonate
what are the types of vaccines?
modified live
killed
recombinant
describe a modified live vaccine
contain virus that has been modified to lose its disease causing ability (attenuation)
describe a killed vaccine
attenuated through a process that results in their death
describe a recombinant vaccine
parts of virus/bacteria genetic sequences that encode immunogenic proteins in animals are isolated
what are the core canine vaccines set by the WSAVA?
distemper
hepatits
parvovirus
what are the core canine vaccines set by the BSAVA?
distemper
hepatitis
parvovirus
leptospirosis
what is the main route of infection of canine distemper virus?
inhalation
what are the clinical signs of canine distemper virus?
respiratory, alimentary, oculo-nasal (2 weeks post infection)
neurological (4 weeks post infection)
hyperkeratosis (3 months post infection)
what is the only treatment available for canine distemper virus?
supportive
what virus causes canine infectious hepatitis?
canine adenovirus 1
what are the main routes of infection of canine infectious hepatitis?
saliva
faeces
what cells does canine infectious hepatitis replicate in? and what does this cause?
hepatocytes
liver failure and jaundice
what is the only treatment for canine infectious hepatitis?
supportive
what are the clinical signs of canine infectious hepatitis?
blue eyes pyrexia lethargy cranial abdominal pain vomiting/diarrhoea
what type of vaccine is canine infectious hepatitis?
live attenuated
what dogs does canine infectious hepatitis mainly occur in?
young (<6 months)
what is the route of infection of canine parvovirus?
faeco-oral
where does canine parvovirus replicate?
rapidly dividing cells (intestinal crypts and bone marrow)
what does intestinal crypt necrosis and villous atrophy lead to?
acute enteritis
what are the clinical signs of canine parvovirus?
lethargy
vomiting
diarrhoea (haemorrhagic)
what type of vaccine is canine parvovirus?
live attenuated
what can be used to diagnose canine parvovirus?
clinical signs
faecal SNAP test