Clinical exams and day 1 skills Flashcards
what are some reasons to vaccinate?
responsible pet ownership maintain healthy pet population reduce deaths reduce zoonosis incidence early detection of clinical conditions encourage client education
why must we wait until MDAs (maternally derived antibodies) have decreased before vaccinating?
will inhibit the development of an immune response in the neonate
what are the types of vaccines?
modified live
killed
recombinant
describe a modified live vaccine
contain virus that has been modified to lose its disease causing ability (attenuation)
describe a killed vaccine
attenuated through a process that results in their death
describe a recombinant vaccine
parts of virus/bacteria genetic sequences that encode immunogenic proteins in animals are isolated
what are the core canine vaccines set by the WSAVA?
distemper
hepatits
parvovirus
what are the core canine vaccines set by the BSAVA?
distemper
hepatitis
parvovirus
leptospirosis
what is the main route of infection of canine distemper virus?
inhalation
what are the clinical signs of canine distemper virus?
respiratory, alimentary, oculo-nasal (2 weeks post infection)
neurological (4 weeks post infection)
hyperkeratosis (3 months post infection)
what is the only treatment available for canine distemper virus?
supportive
what virus causes canine infectious hepatitis?
canine adenovirus 1
what are the main routes of infection of canine infectious hepatitis?
saliva
faeces
what cells does canine infectious hepatitis replicate in? and what does this cause?
hepatocytes
liver failure and jaundice
what is the only treatment for canine infectious hepatitis?
supportive
what are the clinical signs of canine infectious hepatitis?
blue eyes pyrexia lethargy cranial abdominal pain vomiting/diarrhoea
what type of vaccine is canine infectious hepatitis?
live attenuated
what dogs does canine infectious hepatitis mainly occur in?
young (<6 months)
what is the route of infection of canine parvovirus?
faeco-oral
where does canine parvovirus replicate?
rapidly dividing cells (intestinal crypts and bone marrow)
what does intestinal crypt necrosis and villous atrophy lead to?
acute enteritis
what are the clinical signs of canine parvovirus?
lethargy
vomiting
diarrhoea (haemorrhagic)
what type of vaccine is canine parvovirus?
live attenuated
what can be used to diagnose canine parvovirus?
clinical signs
faecal SNAP test
what are the non-core vaccinations of dogs?
leptospirosis parainfluenza kennel cough complex herpes rabies
what group of animals is the herpes vaccinated licensed in?
pregnant bitches
what is the route of infection of leptospirosis?
ingestion of infected urine
rodent bites
what are the clinical signs of leptospirosis?
jaundice, haemorrhagic syndrome, uraemia syndrome, chronic active hepatitis
what are the two options for leptospirosis vaccination?
lepto-2 (active against 2 strains)
lepto-4 (active against 4 strains)
what are the benefits of the lepto-2 vaccine?
can give second dose 2-4 weeks after first so able to socialise puppy earlier
what virus is a key component of kennel cough?
canine parainfluenza
from what age can canine parainfluenza vaccine be given?
8 weeks (another dose 2-4 weeks later)
what are the two main components of kennel cough vaccine?
canine parainfluenza
Bordatella bronchiseptica
what type of vaccine is kennel cough?
live attenuated
what is the operator warning for the kennel cough vaccine?
immunocompromised individuals should avoid any contact with the vaccine or vaccinated dogs
what age are the core canine vaccines delivered?
1st - distemper, hepatitis, parvovirus (DHP) at 6-8 weeks
2nd - DHP at at least 10 weeks (2-4 weeks after 1st)
booster at 1 year then every 3 years
what age are the non-core canine vaccines delivered?
leptospirosis and parainfluenza at 8 weeks and then 2-4 weeks later
kennel cough at 8 weeks then both annually
what are the core feline vaccines?
feline panleukopenia virus (FPV)
feline herpesvirus
feline calicivirus
(herpes and calici is cat flu)
what are non-core feline vaccines?
feline leukaemia virus
rabies
what are the routes of infection of cat flu?
nasal
oral conjunctival
(sharing food bowls)
what are the clinical signs of feline calicivirus?
gingivitis/stomatitis
lingual ulceration
transient limp
what are the clinical signs of feline herpesvirus?
chemosis
corneal ulceration
how can cat flu be treated?
supportive
reducing stress
antivirals
what are general clinical signs of cat flu?
rhinitis
nasal discharge
sneeze
what does feline panleucopenia virus attack?
rapidly dividing cells (intestinal epithelium, bone marrow, foetuses)
what is caused by feline panleucopenia attacking intestinal epithelium?
diarrhoea
vomiting
what is caused by feline panleucopenia attacking bone marrow?
panleucopenia
what is caused by feline panleucopenia attacking foetuses?
cerebellar hypoplasia
what is the route of infection of FeLV?
fighting and sharing food bowls (saliva)
what are the clinical signs of FeLV?
reproductive
anaemia
immunosuppression
neoplasia
what are the restart protocols for dog vaccines?
DHPPi require single dose
leptospirosis requires 2nd dose 4 weeks later
what are the requirements of an animal health certificate for travel?
microchipped up to date rabies vaccine supporting documentation (proof of id) tapeworm treatment (certain countries)
how soon after issuing of an AHC does the animal have to travel?
within 10 days
what are the most common vaccines given to horses?
influenza and tetanus
what equine vaccinations are available in the UK?
influenza tetnus herpes strangles rotavirus west nile virus equine viral arteritis
what is the main reason for controlling equine influenza?
the economic impact of outbreaks on the equine industry
describe the morbidity and mortality of equine influenza
high morbidity
low mortality
how many equine influenza vaccines are on the UK market?
3
what equine influenza vaccine contains both clade 1 and 2, hence is the only one to apply with the OiE recommendations?
Proteq-Flu
what vaccine is compulsory for racehorses?
equine influenza
what are the Jockey Club Rules for the influenza vaccine?
horse must have received two primary vaccinations between 21 and 92 days apart
they also require a booster between 150 and 215 days after the second vaccine
how often does a horse need an influenza booster if it is competing under the FEI?
every 6 months
what are the ProteqFlu data sheet dates for vaccine administration?
second jab 4-6 weeks after the first
third jab 5 months after the second
booster every year