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4 MBCHB > REPRO 9 > Flashcards

REPRO 9 Flashcards

1
Q

candida does everyone get symp

A

30% of females are colonised with small number of candida and are asymptomatic

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2
Q

what can cause candida

A 
recent antibiotic therapy 
high oestrogen levels (pregnancy)
poorly controlled DM
immunocomp
decreased CD4
steroids
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3
Q

symp of candida

A

intensely itchy white discharge

cottage cheese

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4
Q

budding - hyphae under microsopcy

A

candida albicans

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5
Q

treatment of candida

A

topical clotrimazole 500mg pessary and dotrimazole 1% cream
or
fluconazole 150mg PO stat and cream

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6
Q

bacteria vagninosis is caused by what

A

gradinella vaginalis

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7
Q

what are the symp in BV

A

asymp in 50%
thin water dc
fishy smell

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8
Q

BV features

A

ph >4.5

clue cells

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9
Q

treatment of BV

A

metronidazole 400mg BD for 7d
or
2g stat

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10
Q

prostatitis symptoms

A

UTI symptoms
lower abdominal pain
pain and tender prostate on examination

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11
Q

ix in prostatitis

A

G+C STI in <35s
MSU for culture and staining
FPU for STIs

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12
Q

treatment of prostatitis

if high cdiff risk

A

ciprofloxacin 500mg BD for 28 days

if high CDiff infection then erimethoprim 200mg BD for 28 days

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13
Q

syphilis is caused by what which does not what

A

treponema pallidum

which does not stain with gram stain

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14
Q

trensmission of syphilis

A

sexual contact, transplacental/birth, parental

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15
Q

primary syphilis symp

rx

A

primary chancre at site of sexual contact 90% genital. painless. non tender local LD

heals without treatment

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16
Q

secondary syphilis

A

snail track ulcers buccal. fever. LD. rash including soles and palms. flu like symptoms. patchy alopecia. condylomatala.

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17
Q

tertiary syphilis

A

granulomatous lesions of skin and bones. ascending aortic aneurysms. paralysis.

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18
Q

late syphilis

A

CVS/neuro cx

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19
Q

investigations - demonstrate of exudate from lesion

A

dark field microscopy or swab of lesion for PCR

20
Q

to see how active the disease is and to monitor it
what serology
what happens after rx

A

VDRL, RPR, IgM

should become negative after rx

21
Q

specific serology to confirm dx

A

TPPA, INNILIA, FTAAS, IgG

stays positive for life

22
Q

in tayside what

A

if positive IgG/IgM then IgM, ELISA, VDRL, TPPA

23
Q

treatment of syphilis

A

2.4 MUB penicillin IM 2 in early and 3 in late

24
Q

follow up in syphilis

A

RPR should be negative or serofast titres should decreased by fourfold in 3-6 months in early

25
Q

what is the jarich-hexheimer reaction

A

fever, rash, tachy after first dose of ABs

release of endotoxins after bacterial death

26
Q

ghonnorhea micro

A

gram neg intracellular diplococcus which is easily phagocytksed by polymorphs and can’t survive outside the body

27
Q

where gonnorhoea

A

mucous membranes: genitourinary, rectum, pharynx

28
Q

symptoms of G in males

A

asymp <10%
yellow/green dc
dysuria

29
Q

symptoms of G in females

A

asymp in 50%
increased or change in dc
dysuria
plevic pain

30
Q

ix for G

A

NAATS/PCR
males FPU females HVS
rectal/throat/eye swab for culture

31
Q

complications of gon

A

endometriosis, PID, infertility, ectopic pregnancy, prostattitis

32
Q

treatment of gon and follow up

A

ceftriaxone 500mg IM and aziathoprine 1g stat PO
ceftriaxone 400mg PO

test of cure in all px

33
Q

what is the commonest STI

A

chlamydia

34
Q

does chlamydia stain with gram stain and if no why

A

no

no peptidoglycan in walls

35
Q

C A-C

A

not sexually transmitted. trachoma - eye infection

36
Q

C D-K

A

genital

37
Q

C L1-L3

A

lymphogranulomatoma venerum. can mimic crohns. MSM

38
Q

PID and chlamydia link

A

PID increases the risk of chlamydia by 10

39
Q

female chlamydia symptoms

A

70% asymp
post coital or inter menstrual bleeding
lower abd pain
dyparuria

40
Q

male chlamydia symptoms

A 
50% asymp
urethreal dc
dysuria
urethritis 
epididmo-orchitis
41
Q

ix for chlamydia

A

NAATS/PCR
males FPU
females HVS/VVS
msm - rectal swab

42
Q

complications of chlamydia

A

PID, fitz Hugh curtis Syndrome, tubal damage, chronic pelvic pan, reiters, ectopic, endometriosis

43
Q

tranmission to neonate chlamydia

A

17% conjunctivitis

20% pneumonian

44
Q

treatment of chlmaydia

if rectal

A

azithromycin 1g stat

doxy 100mg BD for 7 days

45
Q

bad thing about NAATS/PCR

A

have to wait 5 weeks to do test of cure as will detect dead organisms

4 MBCHB (80 decks)

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