REPRO 3

Question 1

genital warts HPV

Answer 1

6+11

Question 2

CIN HPV

Answer 2

16 + 18 70%

12 other high risk types 30%

Question 3

risks for cervical cancer

Answer 3

15-24yo
HPV, increased number of sexual partners, age at first intercourse, long term use of oral contraceptive, no use of barrier protection, smoking, immunosuppression, cervical warts

Question 4

what does screening detect

Answer 4

pre cancerous changes

Question 5

who is screened

Answer 5

25-50 yo 3 yearly

50-64 5 yearly

Question 6

CIN is where
symp
what is it

Answer 6

at transitional zone
asymp
dysplasia of normal cells

Question 7

CIN 1
CIN 2
CIN 3

Answer 7

1/3 of epithelium
middle 1/3
full thickness of epithelium

Question 8

what doe koilocytes indicate

Answer 8

HPV infection

Question 9

HPV vaccine protects against what and is given to who

Answer 9

6, 11, 16 and 18
young girls 11-13 2 doses
MSM, HIV px

Question 10

squamous cancer is it the commonest cancer in females

Answer 10

no breast is

second

Question 11

cervical cancer 
1A1
1A2
1B
2A
2B
3
4

Answer 11

1A1 depth 3mm width 7mm
1A2 depth 5mm width 7mm
1B confined to cervix 
2A vaginal involvement 
2B parametrical involvement 
3 lower vagina/pelvic wall
4 bladder/rectum/mets

Question 12

symptoms of cervical cancer

Answer 12

asymp in early stages
abnormal bleeding, post coital, PMB, contact bleeding, pelvic pain, haematuria, UTIs, ureteric obstruction leading to renal failure

Question 13

cervical cancer early spread where

cervical cancer late spread where

Answer 13

lymph - pelvic and para aortic nodes

blood - liver, lungs, bones

Question 14

cervical cancer treatment

Answer 14

LLETz. radio/chemo. surgery

Question 15

cervical cancer LLETZ bad stuffs

Answer 15

can lead to cervical insufficiency which can lead to preterm labour

Question 16

CGIN originates from where

whats the difference between this and CIN

Answer 16

endocervical epithelium

more difficult to dx on smear

Question 17

endocervical adenocarcinoma risk factors

Answer 17

high socioeconomic class, later onset of sexual activity, smoking HPV esp 18, younger px

Question 18

what has the worst prognosis squamous or adeno cervical cancer

Answer 18

adeno

Question 19

cervical erosion is what

Answer 19

exposure to endocervical tissue to acid environment of the vagina
sqmaous metaplasia common

Question 20

risk factors for cervicsl erosion

symp

Answer 20

hormonal changes - young
Preg. COCP

non purulent vaginal dc
post coital bleeding

Question 21

nabothian follicles are what

Answer 21

endocervical glands that have expanded into cysts

can form masses or polyps

Question 22

what is the risk of cervitis

Answer 22

can cause infertility to due simultaneous silent tube damage

Question 23

causes of cervitis

Answer 23

HIV. chlamydia. follicular cervitis.

Question 24

what is a cervical polyp

symp

Answer 24

bening localsied inflam outgrowh

bleeding if ulcerated

Question 25

does pagets disease of the vulvar have underlying cancer

where does it arise form

Answer 25

no most of the time

sweat glands in skin

Question 26

symp of pagets

rx

Answer 26

crusting rash, tumour cells in epidermis. contains mucin. pain. itch

excise

Question 27

young and VIN

older and VIN

Answer 27

multifocal. recurrent or persistent causing rx problems

greater risk for invasive squamous carcinoma

Question 28

is VIN HPV related

Answer 28

yes often

Question 29

vulvar invasive squamous carcinoma who 
symp
where does it arise from 
what is it 
prognostic factor and prognosis 
rx

Answer 29

older
ulcer or exophytic mass
normal epithelium or VIN
well differentiated
inguinal node spread if yes <60% 5yS if no 90%
radical vulvectomy +/-inguinal lymphadectomy

Question 30

VaIN

Answer 30

may also have cervical and vulvar lesions

Question 31

VA SC

Answer 31

less common than vulvar and cervical

Question 32

vaginal melanoma

Answer 32

rare

may appear as polyp