ENDOCRINE 3

Question 1

diabetes insipisudus cranial is what
symp
cause
rx

Answer 1

decreased secretion of ADH
polururia, polydipsia, nocturne
familial DIDMOAD, acqired - idiopathic, trauma
desmopressin

Question 2

ix for DI

Answer 2

increased plasma osmolarity, decreased urine osmolality >700 excludes
water deprivation test: check 8h before then 4h after giving IMODAUP ur/serum osmol ration >2 normal

Question 3

nephrogenic DI is what

causes

Answer 3

resistant to ADH

genetic, increased Ca decreased K lithium sickle cell, pyelonephritis

Question 4

SIADH primary and secondary
symptoms
treatment

Answer 4

primary - pit
secondary - tumours SCLC/pancreas/prostate, stroke, SAH, meningitis, SSRIs, carb, TB, pneumonia

asymp, depression, lethargy, irritability, muscle cramps, seizures, LOC, coma, near

underlying malignancy, correct slowly, fluid restrictions, democlocycine

Question 5

endocrine and pregnancy DM
GDM
hypothryoid 
hyperthyroid 
PP thyroiditis

Answer 5

FA 5mg. eye checks 
decrease weight. annual fasting glucose 
increase thyroxin by 25mcg
PTU. BBs
small diffuse non tender goitre. 25-60% -> hyperthyroid

Question 6

DKA in under 16s risk
treatment
symp

Answer 6

cerebral oedema
careful fluid resus. insulin 1h after fluids started
charthropathy, skin vascular changes, vascular endothelial pathology

Question 7

hyperthyroid in kids symp
ix
rx

Answer 7

behavioural problems, sleep disturbance, eating difficulties, previous puberty
goitre, increased HR, decreased TSH increased T3T4
BBs, 2y of carb, radio dine, surgery