NEURO 4 Flashcards
treatment of tonic clon
sodium val
lamotrigene
levitiracotam
female and infrequent seizures
lamotrigene as lamot takes 10-12 weeks to nitrate up
females and freq seizures
levitiracotam
absence seizures treatment
sodium val if tonic clonic as well/ethosuxamide
myoclonic treatment
sodium val
clonazepam/lamotrigene
what drug causes dizziness and shouldnt be given in elderly patients
levotiracotram
bilateral symmetrical 3Hz spike and wave pattern
primary generalised - tonic clonic
temporal partial seizure
psychic
frontal seizure
motor
parietal seizure
sensory
occipital focal seizure
eyes
treatment for focal seizures
carbamazapine/lamotrigene
sodium val/oxcarbazepine/levetericotram
add on: gabapentin, prcegablin, tiagabine, zonsimide, clonazepam
phenytoin
enzyme inducer
sodium valproate
weight gain teratogenic alopecia - grows back curly ataxia tremor hep pancreatitis thrombocytopenia
carbemazapine
ataxia
leucopenia and agranulocytosis
SIADH
diplopia
lamotrigene
steven johnsons syndrome
lecetricatoma
mood swings
topiramate
sedation
dysphasia
weight gain
not well tolerated
what drugs can affect women
carbamazepine, oxacarbazepine, phenobarbitol, phenytoin, pronidone, topiramate
how do these drugs affect
what needs to be given if hepatic enzymes are being used in women
alter efficacy of OCP, can’t use implant/POP, increased freq dose of dePO, increase dose of morning after pill
folic acid and vitamin K
types of status
convulsive SE
non convulsive - conscious but in altered state
epilepsia portalis continua - continuous facial seizures - consciousness still preserved
non epileptic seizures
support
councelling
treatment of anxiety/depression
CBT
Dementia MMS
<24
primary demential causes
Allz, huntingtons, picks, lewy
secondary causes of dementia
vascular, SOL, hydrocephalus, metabolic, infection, trauma, drugs/toxins
alzheimers - risk
downs, increase apoldprotein E4
lewy body
progressive
fluctuating level of attention
hallucination
parkinsonism
how can cortical lewy bodies be picked up
immunochemical staining for the protein ubiquitin
huntingotns chromosome
genetics
age
4 defect
ADon
35-50
Picks how long does it last
progressive rapidly
50-60s
may last 2-10 y - median is 7yo
vascular dementia who
middle ages hypertensives
M>W
depression and anxiety
treatment of dementia mild/mod
rivastigamine, donezapil, galantamine
memantine is what and when is it used
NMDA receptor antagonist
mod alz and can’t have acetylcholinesterase inhibitor OR severe alzheimers
normal pressure hydrocephalus triad
urinary incontinance, dementia, abnormal gait
treatment of normal pressure hydrocephalus
risk of this
ventriculoperitoneal shunting
10% - seizures, infection, intracerebral haemorrhage