DERM 4 Flashcards
SSC precursors are what
Bowens is what
SSC inset females\scaly patch/plaque, irregular border, no dermal invasion, lower leg
akitnic keratosis
viral precursors
common. sun exposed sites: scalp, face, hands
viral genital lesions often dysplastic assoc with HPV. HPV found in 50% of invasive SSC penile
SSC in who
symptoms
risk of mets
adverse prognosis
elderly. sun exposed sites
hyperkeratotic lump/ulcer (crusted), grow fast - may be painful/bleed. ear lip and scalp are high risk sites
5% risk of mets
adverse: thickness, lymph/vascular invasion, perineurial spread, scalp/ear/nose
leg ulcer is what ABPI ix venous ulcers arterial ulcers
break in skin over ankles over 4 weeks
ABPI 0.8 to 1.3 normal
<0.8 vascular disease >1.5 calcification
wound swab if exudate, painful, growing, smelly. bloods. patch testing. duplex scan
shallow edge like a beach around malleolar
sharp cliff like edges punched out
treatment for leg ulcers
control pain. elevation
non adherent dressing: absorption hydrocollides. anti bacterial: silver nitrate or monuka honey
desloughing. 4 layer bandage 40mmHg at ankle 25 below knee
compression stockings
60% recurrence rate at 1 year if no protection
porphyrous cutanea tarao is what cause ix symptoms treatment
decreased activity of uroporphyringen decarboxylase -> increased uroporphyrins
alcohol, Hep C, iron overload, increased oestrogen, haemchromatosis
woods lamp
bullous eruption in sunlight. skin fragility. hyper pigmentation. hypertrichosis.
chloroquine. venesection
erythropoietic proto porphyria is what
ix
symptom
decreased activity of ferrocholetase -> increased protophorphyrins
woods lamp
swelling/burning pain. itch. increased risk of gallstones. kids itch/tingle in sun
acute intermittent porphyria
decreased activity of PBG deaminase -> increased uroporphyrins
alcohol. contraception
woods lamp
early adult life. neuro and visceral symptoms. urine turns red on standing
