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4 MBCHB > GI 2 > Flashcards

GI 2 Flashcards

1
Q 
peptic ulcer a break in what 
cause 
symptoms 
when should OGD be done 
diagnosis 
treatment
A

break in mucosal surface >5mm
H Pylori assoc with 95% of DU or 75% of GU, NSAIDs, smoking, alcohol
GORD
>55, new onset, dyspepsia, alarm symptoms
stool antigen, C13 breath test, serology
retest breath test
omeprazole and amox (clarithro) and metho BD 7 days.
Neg H Pylori full dose H2/PPI

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2
Q

what is H Pylori

assoc with what

A

gram neg

PUD, cancer, B cell lymphoma of MALT (eradication of HP causes regression), atopic gastritis

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3
Q 
gastritis is what 
acute causes 
chronic causes 
AI is what 
complications
A

inflammation of stomach causing mucosal injury
trauma, burns, infection
NSAIDs, alcohol, H Pylori
ABs destroy cells - gastric atrophy
pernicious anaemia and metaplasia, ulcers

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4
Q

gastroperesis is what
symptoms
ix
treatment

A

delayed gastric emptying not due to obstruction
fullness, bloating, abdominal pain, N/V, weight loss
oesophageal mam
liquid diet, nutritional support, support, gastric pacemaker

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5
Q

GIST is what
linked with what
treatment

A

mesenchymal tumours
defect of pacemaker cells ICC
Imatinib

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6
Q

MALToma derived from what

involves what

A

mucosa assoc lymphoid tissue

involve B cells in LNs primarily

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7
Q 
gastric cancer in who 
what on histology 
RF
symptoms 
ix
treatment
A 
70-80s, M>F, japan, china, finland
signet cells
Pylori, blood group A, polyps, percinous anaemia, smoking diet
pain, decrease weight, dyspepsia, vom, virchows node
OGD and biopsy
<5cm from OGJ total gastrectomy
5-10cm from OGT subtotal 
chemo pre and post op
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8
Q

commonest cause of gastroenteritis

A

campylobacter

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9
Q

outbreaks

A

salmonella E Coli 0157

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10
Q

viral diahhorea in <3s

A

rotavirus

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11
Q

explosive vom

A

noravirus

stool PCR

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12
Q

travellers diarrhoea dx

cause

A

3 watery stools in 24 hours +/- abd cramps, fever, N/V, blood in stool
E Coli commonest cause

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13
Q

acute food poisoning cause

A

Sa, bacillus ceresus, clostridium perfringes

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14
Q 
E Coli incubations 
how can you get it 
symp
ix
VTEC
A

12-48h
beef, raw milk, water, travellers
watery stools, diarrhoea bloody, abd cramps, N/V
stool toxin
produces venotoxin - haemolytic uraemia syndrome - increased WCC decreased PLT decreased Hb RBC fragments LD > 1.5x normal

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15
Q

staph aureus incur
what producing
symp

A

1-6w
toxin
severe vom

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16
Q

shigella incub
symp
ix

A

48-72h
bloody diarrhoea, vom, and pain
stool culture

17
Q 
campylobacter incub
get it from where
symptoms 
ix
cx
A 
48-72h
poultry, raw milk, poor food prep
sly like symp, abd pain, fever, bloody diarrhoea
stool toxin 
GBS
18
Q

bacillus serous incub
what producing
symp

A

1-6h
toxin
nom within 6 hours of eating rice and diarrhoea >6h later

19
Q

salmonella incubo
get it form wheere
ix

A

12-48h
poultry, raw egg, meat
stool culture

20
Q

typhoid symptoms
ix
treatment

A

fever, systemically, abdominal pain, constipation/diarrhoea
blood cultures
Ceftriaxone/ciprofloxacin
chloramphenicol

21
Q

cholera symptoms

treatment

A

rice water stools, profuse watery diarrhoea, severe dehydration
oral rehydration, azithromycin

22
Q 
giardsis incubation 
spread by what 
ix
symp
treatment
A 
>7d
spread cysts in drinking water 
stool microscopy 
diarrhoea growth retardation in children 
metro/tinidazole
23
Q

cryptosporidium symptoms
ix
rx

A

watery diarrhoea, severe abd pain, >7d
stool sample
self limiting

24
Q

amoebiasis incubation
sympt
ix
rx

A 
>7d
diarrhoea in infants in low income countries 
abd tender and decreased weight 
liver abscess RUQ pain 
stool micro
metro/tinidazole
25
Q

C Diff description

symptom and risk factors

A

GP rod, produces exotoxin - pseudomembranous colitis

constipation and overflow diarrhoea and RF : history of recent <3m or current use of antibiotics, prolonged hospital stay, >65, use of PPI/H2, surgical procedure, immunosuppression

26
Q

ix for C Diff

A

stool toxin

27
Q

severity markers

A

temp >38.5, ileus/colon >6cm on AXR/CT/toxic megacolon/pseuodomembranous colitis, WBC >15x 10^9, CR >1.5 x normal, persisting CDI despite 2 courses of ABs

28
Q

second episode within 8 weeks severe/nonsevere

A

Flucloxacillin 200mg BD for 10 days

4 MBCHB (80 decks)

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