CARDIO 1 Flashcards
diagnosis of hypertension in clinic stage 1
2
malignanant
over 140/90
over or equal to 160/100
SBP>=180 DBP >=110
causes of primary hypertension
causes of secondary hypertension
usually occurs with age
glomerulonephritis, polycyctic kidney, RAS, hyperaldosterornism, cushings, phaeo, acromegaly, hyperparathyroid/hyperthyroid, steroids, pregnancy, OCP, NF, kidney tumours (JGCT), withdrawal of anti hypertensives
symptoms of hypertension
asymptomatic in primary
features of secondary cause
malignant: neuro, cardio, renal, hypertensive retinopathy, aneurysms, seizures, proteinuria etc
ABPM how does it work
how does HBPM work
ABPM takes two measurements every hour per day. average of 14 readings
seated two consecutive readings taken 1 minute apart twice daily. need 4-7 days. disregard D1 readings and use average
if ABPM/HBPM is <135/85
>=135/85
>=150/95
monitor
if over 80 and target organ damage, cardiovascular disease, renal disease, DM or 10 year cardiovascular risk if 20% or over
drugs
other investigations is suspected secondary cause (young) or malignant presentation
when should patients be referred
USS for RAS/PKD 24 hour urinary metanephrines dexa suppression test thyroid function tests IgF1/MRI
40 or under to exclude secondary cause
general measures for hypertension
decrease salt 3-6mg/day, decrease caffeine, lifestyle
if resistant a potassium of what
can’t give thiazide
<4.5 add spironolactone
>4.5 thiazide like diuretic
alpha blockers or beta blockers
targets for blood pressure
emergency treatment of high blood pressure
under 60 target is 140/90
over 80 150/90
diabetic <140/80 end organ damage present <130/80
IV Labetalol 20mg
IV Nicardipine 5mg/hour
causes of heart failure
symptoms includng
coronary artery disease. valvular disease. myocarditis. sarcoidosis. amyloidosis. congenital. endocrine. familial. pregnancy
SOB. orthopnoea. paroxymasl nocturnal dyspnoea. decreased exercise tolerance. fatigue. ankle swelling. increased JVP. hepatojugular reflexes. third HS. murmurs
ix for heart failure
what is the gold standard
urinalysis and urea and creatinine for renal failure
CXR:heart failure signs/rule out lung disease
ECG: Q waves, LBBB, atrial fibrillation
BNP <100 unlikely but if ECG abnormal - ECHO
>=100 do echo
CMR
treatment for heart failure first line - what should be given if the heart rate is fast
2
3
4
other
vaccines
what drugs improve mortality in heart failure patients
ACEI and BB. Ivabridine Spironolactone Stop ACE and switch to ARB valsartan Ivabridine Loop dueretics, digoxin, nitrates, hydrazine, ICD, transplant
annual flu vaccine, one off pneumococcal vaccine
ACEI, spiro, BB, hydralazine and nitrates
early complications of MI: pericarditis Mural thrombosis LV wall rupture 3 more
peri: sudden onset of pain and fever 2-3d post
stasis of blood in the akinetic region -> thrombi formation which may embolism
5-10 d post
heart failure. Mitral regurgitation. arrhythmias
late complications of MI:
2
dressles 2-6 w post
ventricular aneurysm 4-6w post. rupture is rare
ix for angina
gold standard
resting ECG, ETT
for patients who can’t do ETT/abnormal ECG MPS and spect
CT angio is gold standard