HAEM 4

Question 1

VWF defic what is it
ix
treatment

Answer 1

hereditary ADom, common, variable severity
increased APTT
V factor concentrate, vasopressin, cryoprecipitate, FFP

Question 2

AITP what is it 
in who 
symptoms 
ix
treatment and when

Answer 2

ABs against antigens on PLT surface

middle aged women and children

recurrent epistaxis, gingival bleeding, mennrohagia

decreased PLT, B film, BM biopsy

PLT <30 -> high dose steroids, immunoglobulins
consider splenectomy

Question 3

reversal of warfarin steps

Answer 3

no action
omit warfarin dose - takes few days to come down
vit K PO/IV 0.5-1mg taked 6-8hours
clotting factors FFP/factors 2,7,9,10 - immediate effect within 15 mins