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4 MBCHB > REPRO 5 > Flashcards

REPRO 5 Flashcards

1
Q

plasma volume increases by how in pregnancy leading to what

A

50%

anaemia

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2
Q

BP does what
GFR
CO

A

goes down in second trim
up leading to decreased CR and UR
increase - systolic ejection murmur

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3
Q

ACEI/ARBs

A

renal hyperplasia

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4
Q

androgens

A

civilisation of females

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5
Q

anti epileptics

A

cardiac, facial , NT

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6
Q

cytotoxic

A

multiple defects, abortion

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7
Q

lithium

A

CDV

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8
Q

methotrexate

A

skeletal

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9
Q

retinoids

A

ear, CDV, skeletal

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10
Q

warfarin

A

limb and facial

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11
Q

tetracycline

A

stains bone and teeth of kids

avoid in children under 8

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12
Q

phenytoin

A

cleft lip and palate

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13
Q

stillbetrol

A

vaginal adenocarcinoma in girls

urological malignancy in boys

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14
Q

valproate

A

NT

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15
Q

warfarin around labour

A

bleed

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16
Q

opiates around labour

A

resp depression - prem closure of DA

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17
Q

SSRI opiates

A

NAS

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18
Q

phenybarbitone in breast feeding

A

suckling difficulties

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19
Q

amiodaron in breast feeding

A

neonatal hypothyroidism

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20
Q

cytotoxic in breast feeding

A

BM suppression

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21
Q

BZDs in breast feeding

A

drowsiness

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22
Q

bromocriptine in breast feeding

A

surpasses lactation

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23
Q

rx for N/V

A

cyclizine

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24
Q

rx for UTI

A

nitro and ceflaxine

trim in 3rd trim

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25
Q

pain rx

heart burn

A

paracetamol

antacids

26
Q

epilepsy in pregnancy why does the seizure rate go up

A

non compliance

changes in plasma concentration - committing and increased clearance

27
Q

what does frequent seizures lead to

A

low IQ, brady, IUD, maternal death

28
Q

treatment of epilepsy

A

5mg FA 3m prior to conception and throughout

vit K 34-36w 20mg PO if taking hepatic enzyme inducers

29
Q

risk of child developing epilepsy

A

5% if mum/dad
15% if both mum and dad
10% if sibling and mum/dad

30
Q

anti epileptics SE

A

NTD, orofacial, cardiac,

fetal anticonvulsant syndrome: dysmorphic features, hypo plastic nails and distal digits

31
Q

stopping phenobarbital

A

neonatal withdrawal convulsions

32
Q

scans during epilepsy

A

detailed metal scan at 18-20w

detailed cardio scan at 22w

33
Q

cs when in epilepsy

A

recurrent gen seizures in late pregnancy or labour

34
Q

post partum in epileptic mothers

A

neonates IM 1mg vit k

35
Q

pre existing DM leads to what in pregnancy

A

poorer control

renal and eye deterioration

36
Q

what DM drug is not safe in pregnancy

A

SUs

37
Q

GDM

A

fasting glucose >=5.6 2hours >=7.8

38
Q

target for fasting

1h after meal 2h

A
  1. 3
  2. 8
  3. 4
39
Q

retinal screening when

A

every trim

40
Q

postnatal follow up of BG

A

stop treatment and moniter for 24 hours

41
Q

fetal macrosomia can lead to what

c section when

A

should dystocia

>4kg

42
Q

polyhydraminoas risk of what

A

preterm, malpresentation, cord collapse

43
Q

polycythaemia risk of what

A

unexplained stillbirth, thrombotic events, jaundice

44
Q

neonatal hypoglycaemia risk of what

A

cerebral palsy

45
Q

IOL when in pre existing DM

GDM on insulin

A

37-18w

38w

46
Q

important to monitor for what in DM

A

PET

47
Q

pregnancy has a what fold risk of VTE

A

10 fold

48
Q

what is the leading cause of maternal death

A

VTE

49
Q

why does pregnancy have a high risk of VTE

A

increase in factors 7, 8, 10, fibrinogen

decrease in protein S

50
Q

low risk for VTE treatment

A

mobilise and keep hydrated

51
Q

intermediate risk for VTE rx

A

consider LMHW proph

52
Q

high risk for VTE rx

A

LMWH proph

53
Q

dose of LMWH in pregnancy and for how long

A

1mg/kg

3m after birth or 6m after beginning of treatment

54
Q

heparin SE

A

haemorrhage, h/s, osteopenia, heparin induced thrombocytopenia

55
Q

warfarin SE

A

teratogenic, haemorrhage

56
Q

when should heparin be stopped

planned delivery what

A

24 before

give proph dose 12h before

57
Q

hypothyroid rx

A

increase levothyroxin by 25-50mcg in first trim

58
Q

hyperthyroid why does it get worse in first trim

A

because of HCG

59
Q

risks of hyperthyroid

A

IUGR, prem, thyroid storm

60
Q

rx for hyperthyroid

A

PTU

61
Q

thyroid and pregnancy monitoring

A

TFTs every trim

62
Q

anaemia when to give oral iron at booking

at 28 weeks

A

<11g/dl

<10.5

4 MBCHB (80 decks)

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