Renal Impairment Flashcards

1
Q

What are the nephrotoxicity drugs?

A
ACEi
Aciclovir
Aminoglycosides 
Aminosalicylates
Amphotericin B
Ciclosporin 
Cephalosporins 
Cyclophosphamide 
Lithium
Methotrexate 
NSAIDs 
Quinolones
Tacrolimus
Tetracyclines 
Vancomycin
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2
Q

What are the signs of acute kidney injury?

A
Reduced urine output
Fluid retention - swelling of ankles 
Dehydration
Nausea and vomiting
Fatigue
High blood pressure
Confusion
Slight backache
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3
Q

What are the lab results for AKI?

A

Reduced eGFR
Creatinine clearance reduced
High serum creatinine

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4
Q

What drugs should be stopped temporarily during any illness that can result in dehydration?

A

Diuretics
ACEi/ARB
Metformin
NSAIDs

Restart when well

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5
Q

What are the drugs that colour urine red?

A

Dantron
Doxorubicin
Levodopa

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6
Q

What are the drugs that colour the urine pink or orange?

A

Phenindione

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7
Q

What are the drugs that colour urine red-orange?

A

Rifampicin

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8
Q

What drugs colour urine blue?

A

Triamterene

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9
Q

What drugs colour urine orange?

A

Sulfasalazine

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10
Q

What are the drugs that colour stools black/tarry?

A

Iron

Bismuth

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11
Q

What drugs colour urine yellow-brown?

A

Nitrofurantoin

Senna

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12
Q

What drugs colour urine brown?

A

Prostaglandin analogues

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