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Pre-reg Exam 2021 > Bladder And Urinary Disorders > Flashcards

Bladder And Urinary Disorders Flashcards

1
Q

What drugs are first line for urge incontinence?

A 
Antimuscarinics 
Oxybutynin
Tolterodine
Solifenacin
Darifenacin
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2
Q

What drugs are second line for urge incontinence?

A

Beta 3 agonist

Mirabegron

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3
Q

What is cautioned in mirabegron use?

A

QT interval prolongation

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4
Q

What is contraindicated in mirabegron use?

A

Severe uncontrolled hypertension

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5
Q

What is used for stress incontinence?

A

Duloxetine

Moderate to severe stress incontinence in women only. Avoid abrupt withdrawal

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6
Q

What is the first line for nocturnal enuresis in children?

A

Enuresis alarm

Continue until 2 weeks of uninterrupted dry nights

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7
Q

What is the second line treatment for nocturnal enuresis in children?

A

Desmopressin in 5+ years

Do not give intranasally

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8
Q

What are the side effects of desmopressin?

A

Hyponatraemic convulsions

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9
Q

What are the counselling points for desmopressin?

A

Avoid fluid overload, restrict fluid intake for 1 hour before and 8 hours afterwards

Stop in vomiting/diarrhoea until normal fluid balance

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10
Q

What is the mechanism of action of alpha blockers?

A

Relaxes prostatic smooth muscle

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11
Q

What are the alpha blockers?

A 
Terazosin
Doxazosin
Alfuzosin
Tamsulosin
Indoramin
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12
Q

What are the side effects of the alpha blockers?

A

Hypotension - postural hypotension

Intra operative flopping iris syndrome

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13
Q

What are the contraindications of the alpha blockers?

A

Postural hypotension

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14
Q

What are the counselling points for the alpha blockers?

A

Take first dose at bedtime as risk of first dose postural hypotension

Driving can be impaired

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15
Q

What is the mechanism of action of finasteride?

A

5alpha reductase inhibitors

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16
Q

What are the side effects of finasteride?

A

Male breast cancer

Depression and suicidal thoughts

17
Q

What are the counselling points for finasteride?

A

Report breast symptoms

Stop and report depression

Use condoms as excreted in semen

Women of child bearing potential should avoid handling crushed tablets

18
Q

What are the MHRA warnings for finasteride?

A

Rare reports of depression and suicidal thoughts

19
Q

What are the alpha blockers used for?

A

BPH

Pre-reg Exam 2021 (79 decks)

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