Erectile And Ejaculatory Conditions

Question 1

What are the phosphodiesterase type 5 inhibitors?

Answer 1

Sildenafil - 1 hr before
Tadalafil - 30 mins before sex
Vardenafil - 25-60 mins before
Avanafil- 30 minutes before sex

Question 2

What are the prostaglandin analogues?

Answer 2

Alprostadil (not orally)

Urgent medical assistance for prolonged erection lasting more than 4 hours (priapism)

Question 3

How do phosphodiesterase type 5 inhibitors work?

Answer 3

Increases blood flow to penis

Delayed effect with food

Question 4

What are the side effects of sildenafil?

Answer 4

Vasodilation - hypotension, flushing, migraine, headache, dyspepsia, nasal congestion, palpitations, tachycardia

Question 5

What are the contraindications in sildenafil?

Answer 5

Reduced blood perfusion

MI, unstable angina, recent stroke, hypotension, systolic <90 mmHg or taking nitrates

Question 6

What are the interactions with sildenafil?

Answer 6

Low blood pressure, vasodilators
Nitrates 
Alpha blockers
CCBs
Nicorandil