GI Smooth Muscle Spasm

Question 1

What are the causes of GI smooth muscle spasm?

Answer 1

IBS
IBD
Bowel colic in palliative care

Question 2

What is used to treat GI smooth muscle spasm?

Answer 2

Antispasmodic drugs

Question 3

How do antimuscarinics work?

Answer 3

Reduces intestinal motility

Question 4

What are the antimuscarinics used in GI smooth muscle spasm?

Answer 4

Atropine
Dicycloverine
Hyoscine butylbromide - motion sickness
Propantheline bromide

Question 5

What are the antimuscarinic side effects?

Answer 5

Blurred vision
Urinary retention
Constipation 
Dry mouth
Pupil dilation
Drowsiness

Question 6

What are the caution of antimuscarinics?

Answer 6

Susceptibility to angle closure glaucoma
Conditions causing tachycardia
CVD

Question 7

What are the contraindications of antimuscarinics?

Answer 7

Prostatic enlargement
Urinary retention 
Paralytic ileus
Toxic megacolon
Myasthenia gravis
Narrow angle glaucoma

Question 8

What is the MHRA advice for hyoscine butylbromide injection?

Answer 8

Risk of serious adverse effects in patients with underlying cardiac disease

Question 9

How do the antispasmodics work?

Answer 9

Direct relaxants of intestinal smooth muscle

Question 10

What are the antispasmodics?

Answer 10

Mebeverine
Alverine

Peppermint oil

Question 11

What is the counselling for peppermint oil?

Answer 11

Swallow capsules whole

Heartburn
Local irritation of mouth