Renal 4 Flashcards
The relationship between PH and H is
Inverse
Normal ECF H concentration
40 neq
Strong vs weak acid and base characteristic
Strong- completely disassociates
Weak- reversible disassociation
Buffers are most efficient when ___
PH=Pka
3 buffer systems in the body
kidney
lungs
chemical acid base buffer system of buffer fluids
The Pha of bicarb
6.1
For each hco3 that is abosrbed, ___ must be secreted
H
What are type a intercalated cells
eliminate h ions while reabsorbing hco3 during acidosis
Collecting duct
Type b intercalated cells
secrete bicarb while reabsorbing h ions during alkalosis
h and bicarb transporters
Phosphate pk
Effective renal buffer bc 6.8
What cause met alk
excess aldosterone
na depletion w long term diuretic use
whats base excess definition
Amount of acid or base that is required to bring ph to 7.4 with co2 40 and temp 37
What causes hco3 reabsorption/ h secretion
High paco2
high h, low bicard
at2, aldosterone, low ecf volume
hypokalemia
Examples causing met alk
vomiting
hypokalemia
primary aldosteronism with diuretic
met alk is associated with
hypokalemia, hypocalcemia, ventricle arrhythmias, increased dig toxicity, compensatory hypoventilation