Renal 4 Flashcards

1
Q

The relationship between PH and H is

A

Inverse

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2
Q

Normal ECF H concentration

A

40 neq

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3
Q

Strong vs weak acid and base characteristic

A

Strong- completely disassociates
Weak- reversible disassociation

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4
Q

Buffers are most efficient when ___

A

PH=Pka

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5
Q

3 buffer systems in the body

A

kidney
lungs
chemical acid base buffer system of buffer fluids

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6
Q

The Pha of bicarb

A

6.1

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7
Q

For each hco3 that is abosrbed, ___ must be secreted

A

H

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8
Q

What are type a intercalated cells

A

eliminate h ions while reabsorbing hco3 during acidosis
Collecting duct

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9
Q

Type b intercalated cells

A

secrete bicarb while reabsorbing h ions during alkalosis
h and bicarb transporters

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10
Q

Phosphate pk

A

Effective renal buffer bc 6.8

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11
Q

What cause met alk

A

excess aldosterone
na depletion w long term diuretic use

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12
Q

whats base excess definition

A

Amount of acid or base that is required to bring ph to 7.4 with co2 40 and temp 37

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13
Q

What causes hco3 reabsorption/ h secretion

A

High paco2
high h, low bicard
at2, aldosterone, low ecf volume
hypokalemia

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14
Q

Examples causing met alk

A

vomiting
hypokalemia
primary aldosteronism with diuretic

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15
Q

met alk is associated with

A

hypokalemia, hypocalcemia, ventricle arrhythmias, increased dig toxicity, compensatory hypoventilation

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16
Q

What causes elevated agap

A

uremia, ketoacidosis, lactic acidosis
methanol, ethylyne glycol, ASA, paraldehyde

17
Q

If you fix acidosis, k will ___

A

go down
k decreaes .6 for ever .1 in ph

18
Q

Doubling MV ___ cerebral blood flow

A

halves, vice versa

19
Q
A