PRODIGY Inhalation Agents

Question 1

Which inhalation agents produce skeletal muscle relaxation?

Answer 1

Any that can produce a MAC of 1.0
(All except N2O)

Question 2

Which is the only agent that doesn’t increase RAP?

Answer 2

Sevo

Question 3

Volatile anesthetics effects on uterine smooth muscle and blood flow

Answer 3

Decrease x 2

Question 4

Sevo can degrade into ___ and ___

Answer 4

Fluoride
Fluoride will decrease kidneys ability to concentrate urine

Question 5

Things that can decrease MAC

Answer 5

Acidosis
Hypercarbia

Question 6

What increases MAC

Answer 6

Females with red hair- Desflurane

Question 7

How can the CRNA prevent an increase in intracranial pressure?

Answer 7

MAC 0.8

Question 8

Difference between des and iso

Answer 8

Des has fluorine
Iso has chlorine

Question 9

Fluorines in iso, des, and sevo

Answer 9

Iso 5
Des 6
Sevo 7

Question 10

Oil gas coefficient of iso, des, sevo, n2o

Answer 10

99
19
50
1.4

Question 11

BG coefficient of ISO, des, sevo, xenon

Answer 11

1.4
.45
.68
.115

Question 12

Sevo advantage over Des

Answer 12

Less pungent- can caus eless PONV, less coughing, and therefore protecting ICP from rising

Question 13

CPP formula and range

Answer 13

MAP-ICP
100-15=75
60-140

Question 14

How much faster is N2O than N?

Answer 14

34

Question 15

Inhaled agents metabolism

Answer 15

N2O NONE .004%
Des .02%
Iso 0.2%
Sevo 2.0%

Question 16

Which inhaled agent increases HR the most at 1.5MAC?

Answer 16

All, but especially Des

Question 17

How would oil gas coefficient predict potency?

Answer 17

The higher the oil gas, the more potent

Question 18

Which site in the brain is responsible for amnestic effects of anesthesia?

Answer 18

Hippocampus- campos doesn’t want to remember surgery/pregnancy

Question 19

N2O interferes with ____

Answer 19

Vitamin B12

Question 20

Ames test

Answer 20

To see if they are carcinogenic
(negative for n2o, des, iso, sevo)

Question 21

What MAC does sevo produce cardiac preconditioning?

Answer 21

1 MAC but ideally 1.5 MAC
MAC BAR

Question 22

What is overpressuring?

Answer 22

Administering higher partial pressure than the alveolar concentration

Question 23

Which inhalation agents dont cause MH?

Answer 23

xenon
N2O

Question 24

How much can N2O increase the size of a PTX?

Answer 24

Double in 10 minutes
Tripple in 30 minutes

Question 25

What is pungency?

Answer 25

Smell and ability to produce airway irritation

Question 26

Which agent produces the least amount of steal?

Answer 26

Sevo of course

Question 26

Inhalation agents and CMRO2 and CBF

Answer 26

GOOD FOR BRAIN
Decrease
Increase

Question 27

Boiling point of iso, des, Sevo

Answer 27

49
23
59

Question 28

Potency in order (with Oil gas coefficient)

Answer 28

Iso 00
Sevo 50
Des 19
N2O 1.4

Question 29

VRG gets __% of CO

Answer 29

75

Question 30

VRG consists of

Answer 30

Brain
Heart
Kidneys
Liver
GIT
Endocrine organs

Question 31

What type of shunt does VSD and tetrology of falot create?

Answer 31

R to L

Question 32

How do modern agents prevent hepatic degredation?

Answer 32

Fluorination

Question 33

NMDA blockers

Answer 33

Magnesium
Ketamine
N2O
Xenon
Halothane
Enflurane

Question 34

What location do anesthetics block responses to noxious stimuli?

Answer 34

Spinal cord

Question 35

When would you see burst suppression?

Answer 35

Des- 1.5 MAC
Sevo/ Iso- 2 MAC

Question 36

Effects of N2O b12 interference

Answer 36

Megaloblastic changes in bone marrow

Question 37

CSF absorption?

Answer 37

ISO

Question 38

What increases SVR and CMRO2?

Answer 38

N2O

Question 39

Most pungent agent

Answer 39

Des
Not appropriate for induction bc coughing, salivation, laryngospasm, and breath holding

Question 40

When will a patient wake up ? What percent of agent has to be eliminated?

Answer 40

80-90%