Random Kentucky Flashcards
1
Q
Benzos requiring CYP450 vs renal
A
CYP midazolam/ diazepam
Renal m
MLorazepam
2
Q
What is the half life of romazicon?
A
60 minutes
3
Q
Dantrolene MOA
A
Blocks release if CA from SR
4
Q
Dantrolene + CCB
A
Severe hyperkalemia
Severe myocardial depression
5
Q
Overall effect of histamine release
A
Bronchoconstriction
Vasodilation
Increased cap permeability
6
Q
Ketorolac cautions
A
Asthma
Renal insufficiency/ failure
7
Q
Normal and abnormal dibucaine #
A
Normal 70-100
Abnormal < 60
8
Q
How are esters and amides metabolized?
A
Esters- plasma pseudocholinesterases
Amides- liver (cyp450)
9
Q
Local anesthetic metabolism by age
A
Very young and very old= decreased clearance, increased absorption
10
Q
How does age effect MAC?
A
Very young (neonates)- decreases MAC
6 months- peaks
Old- decreased MAC (6% per decade after 40)
11
Q
A
