Pharm Review Flashcards
Which adrenergic receptor is responsible for peripheral vasoconstriction?
a1
Which adrenergic receptor is responsible for positive chronotropy?
B1
Which adrenergic receptor is responsible for bronchodilation?
B2
Which drug is generally only indicated for use in CPR and anaphylactic shock?
Epinephrine
What are catecholamines?
Epi, NE, isoproterenol, Dopamine, Dobutamine (ENIDD)
What catecholamine causes D1 receptor mediated vasoconstriction at high doses?
Dopamine
What three drugs may be used as part of advanced life support?
Epi, atropine, vasopressin
Which vasopressin analogue is considered the drug of choice for tx of clinical bleeding in patients w/vWD?
Desmopressin acetate (DDAVP)
Which vasopressin analogue is used to treat central diabetes insipidus?
DDAVP
What are ddx causes for hypotension?
Hypovolemia, vasodilation, poor CO
What is the drug of choice for hypertension in cats?
Amlodipine
What is the MoA of amlodipine?
Ca channel blocker
What class of drugs interfere with RAAS?
ACE inhibitors
What class of drugs is the mainstay treatment for pulmonary hypertension?
Phosphodiesterase inhibitors
What drugs are used in tx for emergency hypertension?
Nitroprusside, nitroglycerine (vasodilators)
What drug is used for treating hypertension assoc. w/pheochromocytoma?
Phenoxybenzamine
What is the drug of choice for treatment of pulmonary hypertension?
Sildenafil (Viagra)
What is the drug of choice for treating hyperthyroidism in cats?
methimazole
What is the drug of choice for positive inotropic support in CHF d/t DCM?
Pimobendan
How do you treat V-tach?
Lidocaine
What is the MoA of lidocaine?
Class 1B sodium channel blocker
What is the diuretic of choice for treatment of cardiogenic pulmonary edema?
Furosemide
What drug is used in a tenison test for diagnosis of myasthenia gravis?
Edrophonium
What is the drug of choice for maintenance therapy of myasthenia gravis?
Pyridostigmine
Which NSAIDs are non-selective COX inhibitors?
Phenylbutazone, flunixin meglumine
Which NSAID is a COX-1 selective inhibitor?
Aspirin
Which breeds are considered most sensitive to pheothiazine effets?
Brachycephalics
What is the reversal agent for benzodiazepines?
Flumazenil
What is the most common side effect seen with acepromazine adminstration?
Hypotension
Phenothiazines cause enlargement of which organ?
Spleen
What is the reversal agent for opioids?
Naloxone
Which opioid receptor provides sedation?
Kappa
What is the reversal agent for dexmedetomidine?
Atipamezole
How do you reverse xylazine?
Yohimbine
What is the emetic of choice in cats?
Xylazine
What is the emetic of choice in dogs?
Apomorphine
Which drugs are useful in the control of neuropathic pain?
Gabapentin, amantadine
Are dissociative anesthetics (NMDA antagonists) reversible?
No
What is the MoA of propofol, alfaxalone, and etomidate?
GABA agonists
Lower MAC = _____ potency
Higher
How do you treat a seizure while it’s happening?
Diazepam
What anti-epileptic drug is contraindicated for use in cats?
Bromide (causes asthma in cats)
Which anti-epileptic drug has no hepatic metabolism?
Levetiracetam
What is the drug of choice for seizures d/t hepatic encephalopathy?
Levetiracetam
What is the drug of choice for supplementation of thyroid hormone d/t hypothyroidism in dogs?
Levothyroxine
Mitotane is used to treat _____adrenocorticism
Hyper (Cushing’s)
Which chemo drug is assoc. w/risk of hemorrhagic cystitis?
Cyclophosphamide
What prokinetic do you want to use in rabbits?
Cisapride (affects lower GIT)
Which antacid is given to animals with mast cell tumors?
Famotidine/ranitidine (H2 blocker)
What is the main indication for use of pancrelipase?
EPI
What drug is an antioxidant used to replenish tissue glutathione in cases of hepatotoxicity?
N-acetylcystine
Which receptor, when acted on, can cause SLUDD signs?
M1 (muscarinic)
What is the MoA of diphenhydramine?
H1 antagonist
