Clin Path Review 3

Question 1

Macrocytic anemia indicates what type of anemia and why?

Answer 1

Regenerative b/c immature RBCs are a little bigger than mature RBCs

Question 2

Microcytic anemia indicates what type of anemia?

Answer 2

Iron deficiency

Question 3

Microcytic anemia is often seen with what condition?

Answer 3

Chronic blood loss

Question 4

What does polychromasia indicate?

Answer 4

Regenerative anemia d/t blood loss/destruction

Question 5

Blueish color of young RBCs

Answer 5

Polychromasia

Question 6

What does hypochromasia suggest?

Answer 6

Not enough Hb

Question 7

Fragmented RBCs are called _____

Answer 7

Schistocytes

Question 8

What causes echinocytes?

Answer 8

E-lyte imbalances, non-specific disease, rattlesnake venom

Question 9

Seen in blood smear d/t changes in lipid concentrations in RBC membrane

Answer 9

Acanthocytes

Question 10

What disease will produce acanthocytes?

Answer 10

Cats w/hepatic lipidosis, dogs w/hemangiosarcoma

Question 11

What type of anemia produces keratocytes?

Answer 11

Iron deficiency anemia

Question 12

What cell morphology looks like a manta ray mouth?

Answer 12

Keratocytes

Question 13

What causes schistocyte formation (RBC fragmentation)?

Answer 13

Intravascular trauma (DIC, tumors), or iron deficiency anemia

Question 14

What does the presence of a spherocyte suggest?

Answer 14

IMHA

Question 15

Small RBC that lacks central pallor

Answer 15

Spherocyte

Question 16

Shifting of Hb to one side of the cell

Answer 16

Eccentrocytes

Question 17

What causes formation of eccentrocytes?

Answer 17

Oxidative damage (ie onions, garlic, etc)

Question 18

What other blood abnormality is seen in conjunction with eccentrocytes?

Answer 18

Heinz bodies

Question 19

What causes heinz body anemia?

Answer 19

Oxidative damage

Question 20

What are extrinsic causes oxidative damage to RBCs in cats?

Answer 20

Acetaminophen, propylene glycol

Question 21

What illnesses can cause heinz body production in cats?

Answer 21

Lymphoma, hyperT, diabetes

Question 22

What drugs can cause heinz body anemia in dogs?

Answer 22

Cephalosporins

Question 23

Ingestion of this metal can cause heinz body anemia in dogs and cats

Answer 23

Zinc

Question 24

What plant causes heinz body anemia in horses?

Answer 24

Wilted red maple leaves

Question 25

What drug causes heinz body anemia in horses?

Answer 25

Phenothiazine

Question 26

What foods cause heinz body anemia in cattle?

Answer 26

Kale, onions

Question 27

What metal causes heinz body anemia in sheep?

Answer 27

Copper tox

Question 28

Abnormal aggregation of ribosomes that appear as small basophilic granules

Answer 28

Basophilic stippling

Question 29

In what species is basophilic stippling normal?

Answer 29

Ruminants

Question 30

A significant amount of basophilic stippling in a small animal might indicate what type of poisoning?

Answer 30

Lead poisoning

Question 31

Normally seen w/regenerative anemias and normal with non-functioning spleens or splenectomy patients

Answer 31

Howell-jolly bodies

Question 32

Seen with increased corticosteroids

Answer 32

Howell-jolly bodies

Question 33

If howell-jolly body presence is out of proportion to the degree of anemia, what type of poisoning should be considered?

Answer 33

Lead poisoning

Question 34

Rouleaux formation suggests what disease in small animals?

Answer 34

IMHA