Endocrine Review 2 Flashcards
What endocrine disease causes bilaterally symmetrical alopecia?
Hyperadrenocorticism (Cushing’s)
What endocrine disease produces a pendulous abdomen?
Hyperadrenocorticism (Cushing’s)
Calcinosis cutis is a consequence of which endocrine disease?
Hyperadrenocorticism (Cushing’s)
What is the typical reason that a Cushingoid dog presents to the vet?
“Being old” and urinating in inappropriate places
Excessive panting can be a clinical sign of which endocrine disease?
Hyperadrenocorticism (Cushing’s)
What type of hyperadrenocorticism (Cushing’s) is most common?
PDH (80-85% of cases)
Pituitary dependent hyperadrenocorticism (Cushing’s) is caused by what?
ACTH-secreting tumor
What is the ratio of adrenal carcinoma: adrenal adenomas that cause hyperadrenocorticism (Cushing’s)?
50/50
How common are bilateral adrenal tumors?
Rare
If bilateral adrenal tumors are present, how will they present?
Nonfunctional on one side and pheochromocytoma of opposite adrenal
What test do ALL suspect cushingoid dogs have performed?
Urine culture
How do you dx hyperadrenocorticism?
LDDST
How does dexamethasone administration affect a normal dog?
Normally decreases ACTH
No suppression at 8h on a LDDST indicates what disease?
Hyperadrenocorticism (Cushing’s)
How do you ddx PDH from AT?
No suppression @ 8h + 50% suppression @ 4h = PDH
What is the test of choice for iatrogenic Cushings/Addison’s?
ACTH stim test
How does ketoconazole help treat hyperadrenocorticism (Cushing’s)?
Decreases circulating cortisol concentrations