Clin Path Review 4

Question 1

When does a regenerative anemia d/t blood loss NOT have normal RBC morphology?

Answer 1

Hemangiosarcoma in dogs

Question 2

Does blood loss cause thrombocyotopenia?

Answer 2

NO NO NO

Question 3

What is the most common way in which blood is chronically lost?

Answer 3

Via intestine

Question 4

Microcytosis, keratocytes, regenerative anemia, low serum iron

Answer 4

Iron deficiency anemia

Question 5

How will iron storage differ with anemia of inflammatory disease?

Answer 5

High serum iron

Question 6

What causes extravascular hemolysis?

Answer 6

Phagocytosis of RBCs in spleen, liver, etc

Question 7

What diseases cause extravascular hemolysis?

Answer 7

IMHA, heinz body anemia, RBC parasites, hypophosphatemia

Question 8

What are signs of blood destruction?

Answer 8

Anemia, splenomegaly, normal TP

Question 9

IMHA is assoc. w/what in horses?

Answer 9

Penicillin, Clostridium, neoplasia

Question 10

IMHA is assoc. w/what in cats?

Answer 10

Mycoplasma, FeLV, neoplasia

Question 11

Which dog breed is at highest risk for IMHA?

Answer 11

Cocker spaniels

Question 12

Thrombocytopenia, inflammatory leukogram, azotemia, Spherocytes

Answer 12

IMHA

Question 13

Spherocytes can be seen in horses with what infection?

Answer 13

Clostridial infections

Question 14

What do IMHA animals usually die of?

Answer 14

Thromboembolism

Question 15

How do you treat IMHA?

Answer 15

Glucocorticosteroids, fluids

Question 16

Direct antiglobulin test done to detect IMHA as long as agglutination is not present

Answer 16

Coomb’s test

Question 17

Maternal antibodies against neonate’s blood group antigen

Answer 17

Neonatal isoerythrolysis

Question 18

Which erythrocyte parasites cause intravascular hemolysis?

Answer 18

Babesia and Theileria

Question 19

Common, serous cause of severe anemia in cats that is transmitted horizontally and vertically

Answer 19

Mycoplasma haemofelis

Question 20

How do you treat Mycoplasma haemofelis infection?

Answer 20

Doxycycline for 3 weeks

Question 21

Causes severe anemia in baby pigs and is assoc. w/poor weight gain in adult pigs

Answer 21

Mycoplasma haemosuis

Question 22

How do you treat baby pigs with M. haemosuis?

Answer 22

Long-acting oxytetracycline

Question 23

Tick-borne rickettsial infection that can cause fatal hemolytic anemia d/t immune-mediated destruction

Answer 23

Anaplasmosis

Question 24

Causes severe disease and hemolytic anemia and is commonly mistaken for IMHA

Answer 24

Babesiosis

Question 25

How do you treat Babesiosis?

Answer 25

Imidocarb disproprionate

Question 26

Protozoans that cause hemolytic anemia in ruminants

Answer 26

Theileriosis

Question 27

Piroplasm lives in RBCs of ruminants

Answer 27

Theileriosis

Question 28

Protozoan of cats transmitted by ticks and almost always fatal

Answer 28

Feline cytauxzoonosis

Question 29

What stain will dx heinz body anemia?

Answer 29

Wright’s stain and New Methlyne Blue stain

Question 30

Moth ball ingestion causes what type of anemia?

Answer 30

Heinz body anemia

Question 31

How do you treat methemoglobinemia?

Answer 31

Methylene blue

Question 32

Caused by red maple leaf ingestion in horses and nitrite poisoning in cows

Answer 32

Methemoglobinemia

Question 33

Causes postparturient hemoglobinuria in cattle, DM in cats

Answer 33

Copper toxicosis

Question 34

What causes yellow lamb disease?

Answer 34

C. perfringins type A

Question 35

What causes bacillary hemoglobinuria and red water disease in cattle?

Answer 35

C. haemolyticum

Question 36

English springer spaniels can have an autosomal recessive genetic disorder causing _____ deficiency that causes hemolytic anemia

Answer 36

Phosphofrutokinase

Question 37

What dog breeds are genetically predisposed to pyruvate kinase deficiency?

Answer 37

Basenji, beagle, westie, Carin terriers

Question 38

What cat breeds are genetically predisposed to pyruvate kinase deficiency?

Answer 38

Abyssinian, Somali, DSH