Pain Flashcards
(true/false) BDNF is a neurotransmitter
false
What pathway is responsible for fast and localizing pain?
neospinothalamic pathway
What pathway is responsible for slow/gradual pain and dull pain?
paleospinothalamic pathway
What pathways make up the paleospinothalamic pathway?
spinoreticular
spinomesencephalic
spinolimbic
What system is the paleospinothalamic and neospinothalamic pathway a part of?
anterolateral system
What is the reticular formation responsible for?
attention
What structures of the brain are responsible for the afferent part of pain?
- amygdala
- insula
- anterior cingulate cortex
What structures of the brain are responsible for attention and cognititon?
- prefrontal cortex
- basal ganglia
What lobe is the amygdala a part of?
temporal lobe
What is the function of the amygdala?
emotion
What causes neuropathic pain?
Damage to a nerve
(DM, shingles, amputations)
definition: pain that exists AFTER the stimuli causing the pain is gone
chronic pain
What descending systems help with pain modulation?
PAG
locus ceruleus
raphe system
The raphe system inhibits ____ input going to the cortex.
C fiber
definition: pain from the nerve itself
neuropathic pain
(true/false) CRPS is normally caused by a noxious event and is hard to control.
false (not caused by a noxious event)
What are the s/s of type I CRPS?
- pain
- redness
- allodynia
definition: touching an area and causing pain strictly through mechanoreceptors
allodynia
Fibromyalgia affects (males/females) more.
females
What is the s/s of fibromyalgia?
TTP pain
What are the mechanisms that cause chronic pain?
- wind up
- damage to PNS
- reorganization of the CNS
definition: As damage to a nerve tries to regenerate, the axons converge due to not enough myelin separating them (therefore, doubling the effect)
ephaptic transmission
definition: a mild stimulus causes an increase in neurotransmitters within the spinal cord due to sensitization of the pathway
wind up
In allodynia, the _____ will activate the painful pathway.
mechanoreceptor
definition: having trouble distinguishing L from R
Laterality
