packet 11 Flashcards

1
Q

release lysozymes which destroy/digest bacteria
release defensin proteins that act like antibiotics & poke holes in bacterial cell walls destroying them
release strong oxidants (bleach-like, strong chemicals ) that destroy bacteria

A

direct action against bacteria (neutrophil)

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2
Q

Granular; 10-12 microns; 60-70% of circulating WBC

Fastest response of all WBC to bacteria

A

neutrophil

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3
Q

Largest WBC; 12-20 microns, 3-8% circulating WBC
Most migrate into tissues, becomes fixed macrophage
Take longer to get to site of infection, but arrive in larger numbers
Become wandering macrophages, once they leave the capillaries
Destroy microbes and clean up dead tissue following an infection

A

monocyte

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4
Q

Granular (lots of histamine!); 8-10 microns

A

basophil function

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5
Q

Granular; 10-12 microns; 2-4% of circulating WBCs
Leave capillaries to enter tissue fluid
Release histaminase
slows down inflammation caused by basophils
Attack parasitic worms
Phagocytize antibody-antigen complexes

A

eosinophil

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6
Q

20-25% circulating WBC
b cells
t cells
natural killer cells

A

lymphocyte

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7
Q

destroy bacteria and their toxins

turn into plasma cells that produces antibodies

A

B cells (6-9 microns)

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8
Q

attack viruses, fungi, transplanted organs, cancer cells & some bacteria

A

t cells (10-12 microns)

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9
Q

attack many different microbes & some tumor cells

destroy foreign invaders by direct attack

A

Natural killer cells (up to 14 microns)

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10
Q

indicates infection, poisoning, leukemia, chemotherapy, parasites or allergy reaction

A

WBC changes

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11
Q

60-70% (up if bacterial infection)

A

neutrophils

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12
Q

20-25% (up if viral infection)

A

lymphocyte

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13
Q

3 – 8 % (up if fungal/viral infection)

A

monocytes

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14
Q

2 – 4 % (up if parasite or allergy reaction)

A

eosinophil

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15
Q
A

basophil

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16
Q

bodies ability to defend itself against specific foreign material or organisms
bacteria, toxins, viruses, cat dander, etc.

A

immunity

17
Q

Differs from nonspecific defense mechanisms
specificity—-recognize self & non-self
memory—-2nd encounter produces even more vigorous response
Immune system is cells and tissues that produce the immune response
Immunology is the study of those responses

A

acquired and adaptive immunity

18
Q

mature in thymus

A

t cells

19
Q

cells in bone marrow

A

b cells

20
Q

cell-mediated response
killer cells attack antigens
helper cells costimulate T and B cells
effective against fungi, viruses, parasites, cancer, and tissue transplants

A

t cells

21
Q

antibody-mediated response
plasma cells form antibodies
effective against bacteria

A

b cells

22
Q

Molecules or bits of foreign material

A

antigen

23
Q

ability to provoke immune response

A

immunogenicity

24
Q

ability to react to cells or antibodies it caused to be formed

A

reactivity

25
Q

enter the bloodstream to be deposited in spleen
penetrate the skin & end up in lymph nodes
penetrate mucous membrane & lodge in associated lymphoid tissue

A

when antigen get past bodies nonspecific defense

26
Q

smaller substance thatcan not trigger an immuneresponse unless attached tobody protein
lipid of poison ivy

A

hapten

27
Q

small part of antigen that triggersthe immune response

A

epitope

28
Q

Large, complex molecules, usually proteins

A

antigen/epitopes

29
Q

Immune system can recognize and respond to a billion different epitopes – even artificially made molecules
Explanation for great diversity of receptors is genetic recombination of few hundred small gene segments
Each B or T cell has its own unique set of gene segments that codes its unique antigen receptor in the cell membrane

A

Diversity of Antigen Receptors