packet 11 Flashcards
release lysozymes which destroy/digest bacteria
release defensin proteins that act like antibiotics & poke holes in bacterial cell walls destroying them
release strong oxidants (bleach-like, strong chemicals ) that destroy bacteria
direct action against bacteria (neutrophil)
Granular; 10-12 microns; 60-70% of circulating WBC
Fastest response of all WBC to bacteria
neutrophil
Largest WBC; 12-20 microns, 3-8% circulating WBC
Most migrate into tissues, becomes fixed macrophage
Take longer to get to site of infection, but arrive in larger numbers
Become wandering macrophages, once they leave the capillaries
Destroy microbes and clean up dead tissue following an infection
monocyte
Granular (lots of histamine!); 8-10 microns
basophil function
Granular; 10-12 microns; 2-4% of circulating WBCs
Leave capillaries to enter tissue fluid
Release histaminase
slows down inflammation caused by basophils
Attack parasitic worms
Phagocytize antibody-antigen complexes
eosinophil
20-25% circulating WBC
b cells
t cells
natural killer cells
lymphocyte
destroy bacteria and their toxins
turn into plasma cells that produces antibodies
B cells (6-9 microns)
attack viruses, fungi, transplanted organs, cancer cells & some bacteria
t cells (10-12 microns)
attack many different microbes & some tumor cells
destroy foreign invaders by direct attack
Natural killer cells (up to 14 microns)
indicates infection, poisoning, leukemia, chemotherapy, parasites or allergy reaction
WBC changes
60-70% (up if bacterial infection)
neutrophils
20-25% (up if viral infection)
lymphocyte
3 – 8 % (up if fungal/viral infection)
monocytes
2 – 4 % (up if parasite or allergy reaction)
eosinophil
basophil