NSAID(s)

Question 1

COX 3 is found where

Answer 1

Spinal cord
Brain
Heart

Question 2

What cox inhibitor is associated with side effects of NSAIDs

Answer 2

Cox 3

Question 3

What is the role of NSAIDs in inflammation

Answer 3

It REDUCES inflammation by decrease the vasodilator and increased permeability effect of prostaglandin

Question 4

Traditional NSAIDs targets are ………. vox and Cobix targets are ………

Answer 4

COX1
COX 2

Question 5

State the roles, features of the three types of COX

Answer 5

Cox1

Involved in platelet action
It I’d tissue specific
Implicated in haemostasis

Cox2

It is an inducible enzyme
It is induced by inflammation
It is directly involved with the NSAIDS
Brings about the therapeutic effects of NSAIDs

CoX 3
It is found in the spinal.cord brain and heart

It is involved in pain responses and fever
It’s inhibition is commonly associated with the side effects associated with NSAIDs