Cardiac Arrhythmia Flashcards

1
Q

What does PR interval indicate?

A

Measures Conduction time from atrium to ventricle

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2
Q

What does QRS wave represent

A

The time it takes for all ventricular cells to be excited..
I.e intraventricular conduction time

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3
Q

The electrical activities of the heart control…….. of the heart

A

Rhythm

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4
Q

The mechanical activities control the …….. of the heart

A

Pumping action of the heart

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5
Q

When the mechanical and electrical part of the heart fails respectively it is called

A

Heart failure
Arrhythmia

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6
Q

What is the pathophysiology of Arrhythmia?

A

There’s a change in the membrane potential of cardiac cells which affect the rhythm…

Anti Arrhythmia drugs functions by Modulating the actions of ion channels on the membrane

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7
Q

What forms the electrical conducting system of the heart

A

The pacemaker cells

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8
Q

The pacemaker cells include

A

Bundle of His
Purkinje fibre
SA node
AV node

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9
Q

What is the native pacemaker of the cell

A

SA node is the intrinsic pacemaker of the cell.

It has the highest intrinsic firing rate 60-100times/min

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10
Q

The intrinsic firing activity of the other pacemaker cells are

A

AV node and bundle of His 50-60/min

Purkinje fibre 30-40/min

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11
Q

The other pacemakers overriden by SA node is called

A

Latent pacemaker

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12
Q

Explain override suppression

A

This occurs when the SA node suppresses the intrinsic firing activity of the pacemaker cells and entrains them to fire at the SA nodal firing activity

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13
Q

The two major mechanism in the pathophysiology of cardiac Arrhythmia

A

Change in automaticity
Changes in conductivity

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14
Q

What does the PR interval represent

A

The time it takes for conduction to spread from the the atrium to the ventricles

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15
Q

What does the QRS complex represent

A

Intraventricular depolarization.

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16
Q

What is the QT interval

A

The time it takes for ventricular action potential

17
Q

ST segment represents

A

Plateau phase

18
Q

The intrinsic rate of firing of the SA node is

A

60-100 beats per minute

19
Q

The intrinsic firing activity of the AV node and bundle of His is ……

A

50-60 beats per min

20
Q

The intrinsic firing activity of the Purkinje fibre is

A

30-40 beats per min

21
Q

What is the nernst potential?

A

The difference between an ions nernst potential and the cell membranes potential

22
Q

What results in early after-depolarization

A

This occurs when there is incomplete inactivation of Na + channel or decrease repolarizing potential of k+

23
Q

Example of early after depolarization is seem in…… and it results in ………

A

Congenital QT syndrome results in torsades de pointes

24
Q

What results in delayed after-depolarization

A

When Na+/K+ is shallow
Ca+ conc is high
B adrenergic stimulation
Digitalis glycoside toxicity

25
Q

Delayed after-depolarization results in tachycardia and extra stole if it results in ………….

A

Another DAD