Local Analgesics Flashcards
1
Q
The ester anaesthesic include
A
Tetracaine(pontocaine)
Benzocaine
Procaine
Cocaine
2
Q
The LA used in ophthalmology procedures include
A
Tetracaine ( pontocaine)
3
Q
Describe the MOA of LA
A
They are lipophillic, weak bases that exist as salts.
They associate with bases and acids in the body.
The have the ability to exist in the uncharged form and cationic form
The enter the cytoplasm and form charged ions and bind Na+ channel
They can also bind through lateral hydrophobic binding
4
Q
Most LA function at a pH of ………
A
7.5 -9
