Anti Angina Drugs

Question 1

What is the primary goal of anti-angina drugs?

Answer 1

To relieve or prevent angina symptoms by improving blood flow to the heart.

Question 2

True or False: Anti-angina drugs are used to treat high blood pressure.

Answer 2

False

Question 3

Which class of anti-angina drugs work by dilating blood vessels to increase blood flow to the heart?

Answer 3

Calcium channel blockers

Question 4

What is the main mechanism of action for nitrates in treating angina?

Answer 4

They dilate blood vessels to increase blood flow to the heart.

Question 5

Which type of anti-angina drug is commonly used as a first-line treatment for stable angina?

Answer 5

Beta blockers

Question 6

What is the primary adverse effect of nitrates?

Answer 6

Headache

Question 7

Which anti-angina drug class should be avoided in patients with heart failure?

Answer 7

Calcium channel blockers

Question 8

What is the main goal of using anti-angina drugs in patients with unstable angina?

Answer 8

To prevent heart attacks

Question 9

True or False: Anti-angina drugs can help reduce the frequency and severity of angina attacks.

Answer 9

True

Question 10

Which anti-angina drug class is known for its negative inotropic effects?

Answer 10

Beta blockers

Question 11

What is the primary mechanism of action for beta blockers in treating angina?

Answer 11

They reduce the heart rate and workload on the heart.

Question 12

Which anti-angina drug class works by inhibiting the action of angiotensin-converting enzyme (ACE) to reduce blood pressure?

Answer 12

ACE inhibitors

Question 13

What is the main side effect of calcium channel blockers?

Answer 13

Peripheral edema

Question 14

True or False: Anti-angina drugs are used to treat coronary artery disease.

Answer 14

True

Question 15

Which anti-angina drug class should be avoided in patients with asthma?

Answer 15

Beta blockers

Question 16

What is the primary mechanism of action for ACE inhibitors in treating angina?

Answer 16

They reduce blood pressure and workload on the heart.

Question 17

Which anti-angina drug class is commonly used for variant (Prinzmetal) angina?

Answer 17

Calcium channel blockers

Question 18

What is the main side effect of ACE inhibitors?

Answer 18

Dry cough

Question 19

True or False: Anti-angina drugs are used to treat heart failure.

Answer 19

False

Question 20

Which anti-angina drug class should be avoided in patients with peripheral artery disease?

Answer 20

Beta blockers

Question 21

What is the primary mechanism of action for calcium channel blockers in treating angina?

Answer 21

They relax and widen blood vessels to improve blood flow.

Question 22

Which anti-angina drug class can cause reflex tachycardia as a side effect?

Answer 22

Nitrates

Question 23

What is the main side effect of beta blockers in treating angina?

Answer 23

Bradycardia

Question 24

True or False: Anti-angina drugs are used to treat arrhythmias.

Answer 24

False

Question 25

Factors that can lead to increased oxygen consumption in the heart include

Answer 25

Increased; heart rate
Contractility
Preload
Afterload

Question 26

Factors that can lead to decreased blood flow to the heart include

Answer 26

Vasospasm
Fixed stenosis
Thrombosis

Question 27

Classify angina based on reduced coronary blood flow

Answer 27

Printzmetal’s variant angina
Vasospasm
Supply ischemia

Chronic stable
Fixed stenosis
Demand ischemia

Unstable
Thrombosis
Supply ischemia

Question 28

Describe the MOA OF nitrates

Answer 28

Nitrate to NO

NO activates guanylyl cyclase
GC converts GTP to cGMP
cGMP activates cGMP-dependent protein kinase
CGMP-dependent protein kinase activates MLC Phosphates.

This then cleaves Phosphate from MLC

This results in relaxation and Decreased venous return to the heart