Anti Angina Drugs Flashcards

1
Q

What is the primary goal of anti-angina drugs?

A

To relieve or prevent angina symptoms by improving blood flow to the heart.

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2
Q

True or False: Anti-angina drugs are used to treat high blood pressure.

A

False

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3
Q

Which class of anti-angina drugs work by dilating blood vessels to increase blood flow to the heart?

A

Calcium channel blockers

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4
Q

What is the main mechanism of action for nitrates in treating angina?

A

They dilate blood vessels to increase blood flow to the heart.

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5
Q

Which type of anti-angina drug is commonly used as a first-line treatment for stable angina?

A

Beta blockers

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6
Q

What is the primary adverse effect of nitrates?

A

Headache

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7
Q

Which anti-angina drug class should be avoided in patients with heart failure?

A

Calcium channel blockers

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8
Q

What is the main goal of using anti-angina drugs in patients with unstable angina?

A

To prevent heart attacks

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9
Q

True or False: Anti-angina drugs can help reduce the frequency and severity of angina attacks.

A

True

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10
Q

Which anti-angina drug class is known for its negative inotropic effects?

A

Beta blockers

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11
Q

What is the primary mechanism of action for beta blockers in treating angina?

A

They reduce the heart rate and workload on the heart.

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12
Q

Which anti-angina drug class works by inhibiting the action of angiotensin-converting enzyme (ACE) to reduce blood pressure?

A

ACE inhibitors

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13
Q

What is the main side effect of calcium channel blockers?

A

Peripheral edema

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14
Q

True or False: Anti-angina drugs are used to treat coronary artery disease.

A

True

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15
Q

Which anti-angina drug class should be avoided in patients with asthma?

A

Beta blockers

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16
Q

What is the primary mechanism of action for ACE inhibitors in treating angina?

A

They reduce blood pressure and workload on the heart.

17
Q

Which anti-angina drug class is commonly used for variant (Prinzmetal) angina?

A

Calcium channel blockers

18
Q

What is the main side effect of ACE inhibitors?

A

Dry cough

19
Q

True or False: Anti-angina drugs are used to treat heart failure.

A

False

20
Q

Which anti-angina drug class should be avoided in patients with peripheral artery disease?

A

Beta blockers

21
Q

What is the primary mechanism of action for calcium channel blockers in treating angina?

A

They relax and widen blood vessels to improve blood flow.

22
Q

Which anti-angina drug class can cause reflex tachycardia as a side effect?

A

Nitrates

23
Q

What is the main side effect of beta blockers in treating angina?

A

Bradycardia

24
Q

True or False: Anti-angina drugs are used to treat arrhythmias.

A

False

25
Q

Factors that can lead to increased oxygen consumption in the heart include

A

Increased; heart rate
Contractility
Preload
Afterload

26
Q

Factors that can lead to decreased blood flow to the heart include

A

Vasospasm
Fixed stenosis
Thrombosis

27
Q

Classify angina based on reduced coronary blood flow

A

Printzmetal’s variant angina
Vasospasm
Supply ischemia

Chronic stable
Fixed stenosis
Demand ischemia

Unstable
Thrombosis
Supply ischemia

28
Q

Describe the MOA OF nitrates

A

Nitrate to NO

NO activates guanylyl cyclase
GC converts GTP to cGMP
cGMP activates cGMP-dependent protein kinase
CGMP-dependent protein kinase activates MLC Phosphates.

This then cleaves Phosphate from MLC

This results in relaxation and Decreased venous return to the heart