Anti Tussives Flashcards
1
Q
The nerve fibres implicated in the tussive stimuli are …….
A
Adelta fiber
C fiber
2
Q
Codeine is converted to morphine by the action of ……….. for its antitussive effect and analgesic effect
A
CYP2D6
3
Q
………… % of the population are CYP2D6 poor metabolisers
A
10%
4
Q
Examples of gabapentinoid
A
Gabapentin
Pregabalin
5
Q
What subunit of the calcium channel does gabapentinoid block ……..
A
a2d subunits
6
Q
Levodropropzine acts peripherally inhibiting the ………
A
Vagal C fibers
7
Q
…………. is a long chain polyglycol derivative of procaine
A
Benzonatate
8
Q
Dextrometthorphan inhibits………… receptors
A
NMDA receptor
A 3 B4 receptor
9
Q
Activation of TRVP leads to release of ………….
A
Substance P
Neurokinin A
Calcitonin Gene related peptide
10
Q
……………. Inhibits P2X3
A
Gefapixant
