Anticoagulants Flashcards
1
Q
Why does heparin have no effect on bound thrombin and Xa
A
Platelet releases PF4 which inhibits the action of heparin
2
Q
Clinical indications of heparin at high doses, at subtherapeitic dose
A
Higher than anticoagulant dose- prevents platelet aggregation
Subtherapeutic dose- clears lipemia
Activates lipoprotein lipase
3
Q
What is used in the treatment of venous Thrombosis and pulmonary embolism
A
Heparin LMWH fondaparinux and warfarin