Néphropathies tubulo interstitielles Flashcards

1
Q

Quels sont les signes clinicobio?

A
  • Sensibilité si cause infetieuses, ou lithines
  • leucocyturie
  • Altération des fonctions tubulaires : polyurie, natriurèse obligatoire (pas de réabsorption), faible protéinurie (tamm-horsfall), acidose tubulaire
  • nécrose papillaire
  • irc
  • HTA tardive
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2
Q

echo de NTIchronique?

A

Reins bosselés, asymétriques, uropathie malformative,

calcifications.

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3
Q

histologie?

A

inflammation (granules +/- pathogènes)

Fibrose interstitielle

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4
Q

Causes uro?

A

malformations, RVU, lithiques et infections urinaires à répétition

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5
Q

Causes médicamenteuses?

A

AINS
Li
cisplatine
anticalcineurines.

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6
Q

causes dysimunnitaires?

A

Sarcoïdose (aigu et chq) et SGS (chq)

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7
Q

NTIC au Li

A

longue exposition

acidose tubulaire distale ave diabète insipide

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8
Q

NTIC a la sarcoidose?

A

hypercalcémie et infiltration lymphocytaire des reins (granolumes)

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9
Q

NTIC du SGS

A

2a 7 ans d’évolutionniste
Néphrocalcinose + acidose tubulaire distale
possible atteinte glomerulaire par cryoglobuline

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