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NUR 326 > Liver probs > Flashcards

Liver probs Flashcards

1
Q

Liver functions

A

metabolism and storage of fat, carbs, protein, vitamins, minerals

Drug metabolism, and detox

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2
Q

how does the liver act as a blood volume Reservoir?

A

Distends/compresses to alter circulating blood volume

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3
Q

how does the liver act as a blood filter?

A

Helps purify blood by removing BiliRubin

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4
Q

how does the liver help with blood clotting factors?

A

Prothrombin and fibrinogen

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5
Q

what is the functional unit of the liver?

A

lobule
Hepatocytes – regrow and regenerate

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6
Q

cupfur cells

A

Responsible for removing bacteria and toxins from blood

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7
Q

what is the portal circulation system responsible for?

A

Bringing blood to liver from stomach, intestines, spleen, pancreas

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8
Q

which vein does the blood enter the liver from?

A

Portal vein

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9
Q

how is the liver involved in the first pass effect?

A

Absorbs products of digestion

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10
Q

liver function test

A

AST, ALT, alkaline phosphate
BiliRubin – unconjugated/conjugated
Serum ammonia
Serum protein
Serum albumin
Prothrombin time – PT

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11
Q

which LFTs will elevate with impairment of the liver?

A

Serum ammonia
Prothrombin time
AST, LT, alkaline phosphate

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12
Q

which LFTs will decrease with impairment of the liver?

A

Serum, protein, and albumin

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13
Q

What is jaundice caused by?

A

Increase bilirubin in blood

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14
Q

three classes of jaundice

A

Hemolytic
Hepatocellular
Obstructive

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15
Q

What is hemolytic jaundice from?

A

Increased breakdown of RBCs

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16
Q

why does hepatocellular jaundice occur?

A

Liver, unable to take up/conjugate BiliRubin

17
Q

how does obstructive jaundice occur?

A

Decreased/obstructed bile flow

18
Q

what is BiliRubin the byproduct of

A

Hemoglobin breakdown

19
Q

conjugated bilirubin is what

A

Direct bilirubin

20
Q

Unconjugated bilirubin is what

A

Indirect bilirubin – more common

21
Q

what would be the result of increased BiliRubin or impaired liver function?

A

Elevated indirect bilirubin

22
Q

what occurs when the liver is working but can’t filter BiliRubin out?

A

direct bilirubin
Also, can lead to bile duct obstruction, gall stones

23
Q

s/sx of jaundice

A

dark urine
Increased liver enzymes
Stools can be normal or clay colored
Pruritus
Yellow discoloration of skin and deep tissues

24
Q

what are optimal sites to indicate jaundice?

A

Sclera of eye
Palms/soles of feet
Mucous membranes

NUR 326 (32 decks)

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