Inflammatory disorders

Question 1

rheumatoid arthritis

Answer 1

Auto immune, systemic, chronic

Inflammation disease of synovium – joints lining

Question 2

cause of RA

Answer 2

Unknown
Possible, environmental and genetic exposure

Question 3

risk factors of RA

Answer 3

40-60
Women
Tobacco use

Question 4

patho of RA

Answer 4

autoimmune attack synovial tissue
Lympho/macrophages immune cells activated

rheumatoid factor – auto antibody versus IgG

Formation of immune complexes in activated complement

Destruction of tissue from inflammation

Question 5

what occurs from the progression of RA?

Answer 5

Scar tissue
Cartilage destroyed by osteoclasts
pannus causes erosion, cysts, Fissure development

Question 6

early s/sx RA

Answer 6

fatigue, anorexia, Stiff
* symmetrical
Decreased ROM
Information, Dash heat, swell, tender

Question 7

advanced sx RA

Answer 7

Deformity, swan neck in finger
Disability

Question 8

rheumatoid nodules

Answer 8

Immune mediated, granulomas develop around information of joints and lungs

Subcutaneous, firm

Fibrous tissue with necrotic filling

Question 9

systemic lupus erythematous

Answer 9

autoimmune versus own DNA
Inflammation, multi organ
Acute flareups

Question 10

discoid lupus

Answer 10

Targets skin

Question 11

systemic, lupus

Answer 11

Target organs

Question 12

what type of hypersensitivity reaction is RA and Lupus

Answer 12

Type three

Question 13

risk factors for lupus

Answer 13

Genetic
Female
20-40
African-American
Sun exposure
Allergic to antibiotics
Hormonal factor-estrogen
Tobacco

Question 14

patho of lupus

Answer 14

abnormal immune response
B lymphocytes, hyper active and produce anti-nuclear antibodies

Activated versus DNA
Complex forms
Inflammatory, tissue destruction

Question 15

CNS s/sx lupus

Answer 15

headache
Dizziness
Seizures
Stroke

Question 16

lungs s/sx lupus

Answer 16

Pleuritis
Effusions

Question 17

heart s/sx lupus

Answer 17

myocarditis
Endocarditis

Question 18

kidney s/sx lupus

Answer 18

Nephritis

Question 19

blood vessel s/sx Lupus

Answer 19

Vasculitis

Question 20

blood s/sx lupus

Answer 20

Anemia
Leukopenia
Thrombocytopenia
Clots

Question 21

joints s/sx Lupus

Answer 21

Arthritis

Question 22

Lupus flares

Answer 22

acute exacerbation of symptoms

Fatigue, pain, headache

Question 23

Prevention of lupus, flares

Answer 23

recognize warning signs
avoid triggers, sun, infection
Don’t abruptly stop meds
Stress management

Question 24

sjögren syndrome

Answer 24

seen in both RA and Lupus

Auto immune destruction of any moisture producing gland

Question 25

lacrimal gland sx

Answer 25

Gritty, dry, itchy eyes

Question 26

salivary gland, SX

Answer 26

Fissured, dry tongue