breast cancer Flashcards
what does breast cancer develop from?
Lining in ducts
Overexpress estrogen, receptors
Over expressed human epidermal GF receptor
risk factors of breast cancer
> 50
Prolonged reproductive life – late childbirth >30, late menopause
Obesity – estrogen, stored in fat
nulliparous– no pregnancies
Family, history, ovarian
Ashkenazi, Jew women
BCRA 1 and 2 mutation
BCRA genes
Screening and genetic mutation, testing for high risk, patients with strong family, history in breast or ovarian cancer
which organs can have an increased risk of the gene mutation?
Breast
colon
Prostate – Males
Ovarian
Pancreatic
s/sx breast cancer
Single tumor
Nontender, firm
Regular borders
Adherence to skin/chest wall
Outer/upper quadrant or breast
One swollen breast
Nipple/skin retraction
peau d’orange
Thickening of skin that resembles orange peel
pagets disease
Read crust, Puritis
Tender nipple, cancerous change
When should mammograms be completed?
yearly at 55 and then every other year