liver and pancreas cancer Flashcards
risk factors for hepatocellular carcinoma
cirrhosis
hepatitis B and C
obesity (NASH)
male
signs of hepatocellular carcinoma
jaundice
ascites
hepatomegaly
haemophilia
(presentation usually due to an obstructive mass)
symptoms of hepatocellular carcinoma
abdominal pain (RUQ)
anorexia
weight loss
fatigue
which liver cancer patients can be treated with sorafenib?
those producing alpha-fetoprotein (50% patients)
diagnosis of hepatocellular carcinoma
imaging
histopathology
treatment of hepatocellular carcinoma
surgery
transplant
TACE (trancatheter arterial chemoembolisation) with doxorubicin, cisplatin, or mitomycin C
radiofrequency ablation
risk factors for pancreatic cancer
smoking
obesity
high red meat consumption
diabetes
what percentage of pancreatic cancers are pancreatic adenocarcinomas?
85%
signs and symptoms of pancreatic cancer
adult onset T2DM Trousseau's sign jaundice abdominal/back pain light coloured stools dark urine anorexia
complications of pancreatic cancer
depression
diagnosis of pancreatic cancer
imaging
biopsy
LFTs
treatment of pancreatic cancer
surgery
chemotherapy with gemcitabine
radiotherapy
