brain tumours Flashcards
Information on brain cancer.
which cells do neuroepithelial tumours resemble?
glial cells
from what do paraneoaxial tumours arise?
covering of brain and surrounding structures
risk factors for brain tumours
genetic
more common in children
what are 85-90% of primary brain tumours?
astrocytomas
how do astrocytomas develop?
IDH1 glucose metabolic mutation
catastrophic genetic mutation
what are 5% of primary brain tumours?
oligodendrocytomas
from which cancers do secondary brain tumours commonly come?
lung (39%) breast melanoma renal GI
progression of astrocytoma
pilocytic astrocytoma (good prognosis)
premalignant
anaplastic astrocytoma
glioblastoma multiforme
characteristics of raised ICP headache
headache is worse in morning
relieved by vomiting
leaning forwards makes headache worse
fixed dilated pupil
symptoms of brain tumour
headache
seizures
progressive neurological deficit
what is a medulloblastoma?
primitive small blue cell tumour of cerebellum
more common in children
better prognosis with beta-catenin
complications of brain tumour surgery
nerve damage
when are oligodendrogliomas most common?
in 4th and 5th decade
MRI WHO performance status for brain tumours
- capable of light work
- self catering up to >50% of day
- limited self-care
- bed bound
what can be seen on scans with oligodendrogliomas?
calcification
